Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Fluvoxamine
Drug ID BADD_D00950
Description Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder. Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised of approximately 35,000 patients. It was launched in the US in December 1994 and in Japan in June 1999. As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine.
Indications and Usage Indicated predominantly for the management of depression and for Obsessive Compulsive Disorder (OCD) [FDA Label]. Has also been used in the management of bulimia nervosa [A250].
Marketing Status Prescription; Discontinued
ATC Code N06AB08
DrugBank ID DB00176
KEGG ID D07984
MeSH ID D016666
PubChem ID 5324346
TTD Drug ID D03HFG
NDC Product Code Not Available
Synonyms Fluvoxamine | Fluvoxadura | Fluvoxamin AL | Fluvoxamin beta | Fluvoxamin Stada | Fluvoxamin-neuraxpharm | Fluvoxamin neuraxpharm | Fluvoxamin-ratiopharm | Fluvoxamin ratiopharm | ratio-Fluvoxamine | ratio Fluvoxamine | Fluvoxamina Geminis | Geminis, Fluvoxamina | Fluvoxamine Maleate | Fluvoxamine Maleate, (E)-Isomer | Fluvoxamine, (Z)-Isomer | Luvox | Floxyfral | Fevarin | Dumirox | Faverin | Novo-Fluvoxamine | Novo Fluvoxamine | Nu-Fluvoxamine | Nu Fluvoxamine | PMS-Fluvoxamine | PMS Fluvoxamine | Desiflu | DU-23000 | DU 23000 | DU23000
Chemical Information
Molecular Formula C15H21F3N2O2
CAS Registry Number 54739-18-3
SMILES COCCCCC(=NOCCN)C1=CC=C(C=C1)C(F)(F)F
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Poisoning and toxicityCytochrome P450 2D6P10635T57392Not Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Epistaxis24.07.01.005; 22.04.03.001--
Eructation07.01.02.003--
Erythema multiforme23.03.01.003; 10.01.03.015--
Euphoric mood19.04.02.006--
Extrapyramidal disorder17.01.02.007--
Extrasystoles02.03.02.003--Not Available
Eye disorder06.08.03.001--Not Available
Eye pain06.08.03.002--
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Feeling drunk08.01.09.015--Not Available
Feeling jittery08.01.09.016--Not Available
Flat affect19.04.01.004--Not Available
Flatulence07.01.04.002--
Fracture15.08.02.001; 12.04.02.001--
Furuncle23.09.01.004; 11.02.05.008--Not Available
Gait disturbance08.01.02.002; 17.02.05.016--
Galactorrhoea21.05.02.002; 05.03.04.002--Not Available
Gastritis07.08.02.001--
Gastrooesophageal reflux disease07.02.02.003--
Gastroenteritis11.01.07.004; 07.19.03.001--Not Available
Gastrointestinal carcinoma07.21.03.001; 16.13.04.001--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Gastrointestinal pain07.01.05.005--
Gingivitis11.01.04.013; 07.09.03.003--
Glaucoma06.03.01.002--
Glossitis07.14.01.001--Not Available
Glossodynia07.14.02.001--Not Available
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