Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Fluocinonide
Drug ID BADD_D00925
Description A topical glucocorticoid used in the treatment of eczema.
Indications and Usage A topical anti-inflammatory product for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Marketing Status approved; investigational
ATC Code C05AA11; D07AC08
DrugBank ID DB01047
KEGG ID D00325
MeSH ID D005447
PubChem ID 9642
TTD Drug ID D03ZZK
NDC Product Code 0093-0263; 40032-095; 51672-1279; 51672-1353; 63629-2509; 71085-006; 51552-0056; 52128-176; 51672-1273; 59088-755; 63629-2337; 68071-2667; 68071-4619; 99207-525; 0168-0457; 47781-602; 53002-9202; 63629-2339; 68071-2541; 71085-004; 71205-092; 68462-505; 68788-8105; 71085-005; 0093-0264; 51672-1253; 63629-2338; 0713-0663; 40032-026; 50090-6309; 53002-9201; 68071-2200; 69238-1534; 70771-1375; 0168-0134; 50090-2419; 51862-494; 63629-2508; 69238-1271; 76420-530; 46439-8707; 49452-3161; 0093-0262; 45802-151; 51672-1264; 53002-9200; 63629-2510; 70700-146; 70771-1393; 0713-0664; 62991-2865; 43386-095; 50090-3277; 63187-033; 68071-2202; 70710-1284; 71428-001; 72578-087; 43386-026; 51672-1386; 68071-2808; 33342-320; 0168-0135; 47781-569; 51672-1254
UNII 2W4A77YPAN
Synonyms Fluocinonide | Fluocinolone Acetonide 21-Acetate | Acetonide 21-Acetate, Fluocinolone | Fluocinolone Acetonide 21 Acetate | Fluocinonide FAPG | FAPG, Fluocinonide | Fluocinolide | Lidex | Lidemol | Lyderm | Tiamol | Topsyne | Novoter | Topsym | Topsyn | Klariderm | Metosyn
Chemical Information
Molecular Formula C26H32F2O7
CAS Registry Number 356-12-7
SMILES CC(=O)OCC(=O)C12C(CC3C1(CC(C4(C3CC(C5=CC(=O)C=CC54C)F)F)O)C)OC(O2)(C)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nervous system disorder17.02.10.001--Not Available
Pain08.01.08.0040.000453%
Pruritus23.03.12.001--
Rash23.03.13.0010.000293%Not Available
Rash maculo-papular23.03.13.0040.000267%
Secondary adrenocortical insufficiency05.03.04.012; 14.11.01.014--Not Available
Skin atrophy23.01.05.001--
Skin disorder23.03.03.007--Not Available
Skin exfoliation23.03.07.003--Not Available
Skin irritation23.03.04.009--Not Available
Skin striae23.01.05.002--Not Available
Swelling08.01.03.015--Not Available
Telangiectasia24.03.03.003; 23.06.03.001--
Tongue discolouration07.14.02.006--Not Available
Skin tightness23.03.03.018--Not Available
Chorioretinopathy06.09.01.0060.000267%Not Available
Application site burn12.07.01.038; 08.02.01.038; 23.03.11.013--Not Available
Treatment failure08.06.01.0170.000680%Not Available
Drug-induced liver injury12.03.01.044; 09.01.07.0230.000267%Not Available
Drug ineffective for unapproved indication12.09.02.002; 08.06.01.0380.000680%Not Available
Serous retinal detachment06.09.03.0370.000200%Not Available
Therapy non-responder08.06.01.0630.000133%Not Available
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