Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Fenoprofen calcium
Drug ID BADD_D00878
Description An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Indications and Usage For relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis. Also for the relief of mild to moderate pain.
Marketing Status Prescription; Discontinued
ATC Code M01AE04
DrugBank ID DB00573
KEGG ID D00968
MeSH ID D005279
PubChem ID 64747
TTD Drug ID D03XYW
NDC Product Code 67835-0029; 50090-3572; 55700-853; 22568-1157; 42195-600; 42195-688; 68022-7002; 71335-0307; 63629-8016; 73435-005; 42195-471; 71335-1302; 71335-0805; 0276-0501; 42195-308; 63187-706; 15014-400; 42195-100; 63629-7515
Synonyms Fenoprofen | Fenoprofen Dihydrate, Calcium Salt | Nalgesic | Fenoprofen Calcium | Fenoprofen, Anhydrous, Calcium Salt | Nalfon
Chemical Information
Molecular Formula C30H30CaO8
CAS Registry Number 53746-45-5
SMILES CC(C1=CC(=CC=C1)OC2=CC=CC=C2)C(=O)[O-].CC(C1=CC(=CC=C1)OC2=CC=CC=C2)C(=O)[O-].O. O.[Ca+2]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001--Not Available
Alopecia23.02.02.001--
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anuria20.01.03.002--Not Available
Aphthous ulcer07.05.06.002--Not Available
Aplastic anaemia01.03.03.002--Not Available
Aspartate aminotransferase increased13.03.01.006--
Asthenia08.01.01.001--Not Available
Atrial fibrillation02.03.03.002--
Azotaemia20.01.01.001--Not Available
Blood lactate dehydrogenase increased13.04.02.002--
Breast pain21.05.05.003--
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Cystitis20.03.02.002; 11.01.14.001--
Depression19.15.01.001--
Dermatitis exfoliative10.01.01.004; 23.03.07.001--
Diarrhoea07.02.01.001--
Diplopia17.17.01.005; 06.02.06.002--Not Available
Disorientation19.13.01.002; 17.02.05.015--Not Available
Dizziness24.06.02.007; 02.01.02.004; 17.02.05.003--
Dry mouth07.06.01.002--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspepsia07.01.02.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Dysuria20.02.02.002--
Electrocardiogram abnormal13.14.05.001--Not Available
Fatigue08.01.01.002--
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