Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Etonogestrel
Drug ID BADD_D00852
Description Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]
Indications and Usage Etonogestrel is administered in subdermal implants as long-acting reversible contraception. It is known to be effective in postpartum insertion including breastfeeding women.[A175990] Etonogestrel is part of the long-acting contraceptive implants that prevent pregnancy. The implant's effect can remain for 5 years.[L5698]
Marketing Status approved; investigational
ATC Code G03AC08
DrugBank ID DB00294
KEGG ID D04104
MeSH ID C044815
PubChem ID 6917715
TTD Drug ID D02KIU
NDC Product Code 64918-1500; 78206-145; 71161-147; 63190-0260; 45541-1192; 60870-0475; 63190-0480; 64918-1906; 65089-0053
UNII 304GTH6RNH
Synonyms etonogestrel | 13-ethyl-17-hydroxy-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one | 3-oxodesogestrel | 3-ketodesogestrel | 3-oxo desogestrel | 18,19-dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-11-methylene-, (17-alpha)- | 3-keto-desogestrel | ORG-3236 | Implanon | nexplanon
Chemical Information
Molecular Formula C22H28O2
CAS Registry Number 54048-10-1
SMILES CCC12CC(=C)C3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Postpartum haemorrhage24.07.03.003; 18.06.01.0010.001034%Not Available
Pregnancy18.08.02.0040.002468%Not Available
Premenstrual syndrome17.14.01.019; 21.01.01.007; 19.04.02.0090.003103%Not Available
Pruritus23.03.12.001--
Pruritus genital23.03.12.008; 21.10.01.0020.000917%Not Available
Psychotic behaviour19.03.01.0030.000917%Not Available
Pulmonary infarction24.04.09.001; 22.06.02.0020.000235%Not Available
Pyrexia08.05.02.003--
Radiculopathy17.10.01.0050.000917%
Rash23.03.13.001--Not Available
Rash vesicular23.03.13.0090.000635%Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Scab23.03.03.0040.002750%Not Available
Scar23.03.11.008; 12.01.06.008--Not Available
Screaming08.01.03.099; 19.04.02.0200.000635%Not Available
Seborrhoea23.02.07.0010.000799%Not Available
Seborrhoeic dermatitis23.03.04.018--Not Available
Seizure17.12.03.001--
Sensory loss17.02.07.0070.000987%Not Available
Sexual dysfunction21.03.02.003; 19.08.05.002--Not Available
Sinusitis22.07.03.007; 11.01.13.005--
Skin atrophy23.01.05.0010.001716%
Skin discomfort23.03.03.0060.000799%Not Available
Skin disorder23.03.03.007--Not Available
Skin erosion23.07.03.0020.001199%Not Available
Skin hyperpigmentation23.05.01.0030.001152%
Skin hypertrophy23.01.04.0020.000752%Not Available
Skin irritation23.03.04.0090.004184%Not Available
Skin odour abnormal23.03.03.0120.000799%
Skin striae23.01.05.0020.000353%Not Available
The 6th Page    First    Pre   6 7 8 9 10    Next   Last    Total 14 Pages