Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Etonogestrel
Drug ID BADD_D00852
Description Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]
Indications and Usage For use as a female contraceptive (depot).
Marketing Status Prescription; Discontinued
ATC Code G03AC08
DrugBank ID DB00294
KEGG ID D04104
MeSH ID C044815
PubChem ID 6917715
TTD Drug ID D02KIU
NDC Product Code 65089-0053; 64918-1500; 60870-0475; 78206-145; 71161-147; 63190-0480; 63190-0260; 45541-1192; 64918-1906
Synonyms etonogestrel | 13-ethyl-17-hydroxy-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one | 3-oxodesogestrel | 3-ketodesogestrel | 3-oxo desogestrel | 18,19-dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-11-methylene-, (17-alpha)- | 3-keto-desogestrel | ORG-3236 | Implanon | nexplanon
Chemical Information
Molecular Formula C22H28O2
CAS Registry Number 54048-10-1
SMILES CCC12CC(=C)C3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Arthropathy15.01.01.0030.004125%Not Available
Asthenia08.01.01.001--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Back disorder15.03.01.0140.003300%Not Available
Back pain15.03.04.0050.069292%
Benign intracranial hypertension17.07.02.0010.000825%Not Available
Binge eating19.09.01.0010.000825%Not Available
Bleeding time prolonged13.01.02.0020.000825%Not Available
Blindness17.17.01.003; 06.02.02.001--Not Available
Blindness unilateral17.17.01.016; 06.02.02.0090.000825%Not Available
Blister23.03.01.001; 12.01.06.002--Not Available
Blood bilirubin increased13.03.01.008--
Blood cholesterol increased13.12.01.002--
Blood iron decreased13.11.01.0060.000825%Not Available
Blood oestrogen increased13.10.05.0070.000825%Not Available
Blood pressure increased13.14.03.005--Not Available
Blood prolactin increased13.10.03.002--Not Available
Body temperature increased13.15.01.001--Not Available
Bone pain15.02.01.001--
Breast cancer21.05.01.003; 16.10.01.001--Not Available
Breast discharge21.05.05.0010.004537%Not Available
Breast enlargement21.05.04.0010.003300%Not Available
Breast mass21.05.04.0020.003300%Not Available
Breast pain21.05.05.0030.023097%
Breast swelling21.05.05.0080.002062%Not Available
Breast tenderness21.05.05.0040.020623%Not Available
Burning sensation17.02.06.001; 08.01.09.0290.009899%Not Available
Carpal tunnel syndrome17.09.02.0010.001237%Not Available
Cataract06.06.01.001--
Cellulitis23.09.01.001; 11.02.01.0010.016086%Not Available
The 2th Page    First    Pre   2 3 4 5 6    Next   Last    Total 19 Pages