Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Etonogestrel
Drug ID BADD_D00852
Description Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]
Indications and Usage For use as a female contraceptive (depot).
Marketing Status Prescription; Discontinued
ATC Code G03AC08
DrugBank ID DB00294
KEGG ID D04104
MeSH ID C044815
PubChem ID 6917715
TTD Drug ID D02KIU
NDC Product Code 65089-0053; 64918-1500; 60870-0475; 78206-145; 71161-147; 63190-0480; 63190-0260; 45541-1192; 64918-1906
Synonyms etonogestrel | 13-ethyl-17-hydroxy-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one | 3-oxodesogestrel | 3-ketodesogestrel | 3-oxo desogestrel | 18,19-dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-11-methylene-, (17-alpha)- | 3-keto-desogestrel | ORG-3236 | Implanon | nexplanon
Chemical Information
Molecular Formula C22H28O2
CAS Registry Number 54048-10-1
SMILES CCC12CC(=C)C3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.0010.014848%
Abdominal pain07.01.05.0020.059393%
Abdominal pain lower07.01.05.0100.010311%Not Available
Abdominal pain upper07.01.05.0030.037533%
Abnormal dreams19.02.03.001; 17.15.02.001--Not Available
Abnormal weight gain14.03.02.0100.002062%Not Available
Abortion18.01.01.0010.002887%Not Available
Abortion missed18.01.01.0020.001237%Not Available
Abortion spontaneous18.01.04.0010.072179%Not Available
Abscess11.01.08.0010.001650%Not Available
Abscess bacterial11.02.01.0270.000825%Not Available
Acne23.02.01.0010.046194%Not Available
Affective disorder19.04.04.0010.005362%Not Available
Aggression19.05.01.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Alopecia23.02.02.0010.032584%
Amenorrhoea05.05.01.002; 21.01.02.0010.194677%
Amnesia19.20.01.001; 17.03.02.001--
Anaemia01.03.02.001--
Anaesthesia17.02.07.0020.000825%Not Available
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anger19.04.02.0010.006187%Not Available
Angina pectoris24.04.04.002; 02.02.02.002--
Angioedema23.04.01.001; 10.01.05.009--Not Available
Ankle fracture15.08.03.005; 12.04.01.005--
Anxiety19.06.02.0020.044132%
Arterial thrombosis24.01.01.0020.000825%Not Available
Arthralgia15.01.02.001--
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