Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Etodolac
Drug ID BADD_D00850
Description Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Indications and Usage For acute and long-term management of signs and symptoms of osteoarthritis and rheumatoid arthritis, as well as for the management of pain.
Marketing Status Prescription; Discontinued
ATC Code M01AB08
DrugBank ID DB00749
KEGG ID D00315
MeSH ID D017308
PubChem ID 3308
TTD Drug ID D0N1WU
NDC Product Code 51655-423; 60760-378; 17373-1086; 61919-251; 71335-0126; 43353-918; 51672-4051; 63629-1935; 63187-374; 43063-834; 0185-0687; 55700-592; 63629-8805; 57451-1161; 60429-312; 71335-0982; 50090-3974; 60505-0040; 43353-749; 43063-578; 43063-856; 70518-3116; 55700-757; 60429-244; 60429-315; 43353-753; 71335-0399; 61919-092; 71205-467; 51672-4052; 66267-575; 63187-796; 60760-552; 71335-0602; 68788-7315; 76385-118; 68382-272; 61919-784; 68382-271; 70518-3163; 60429-314; 43353-752; 62559-251; 50090-3963; 68382-273; 60505-0039; 0093-1118; 63187-736; 60429-313; 69238-1342; 63629-8598; 65841-779; 42291-405; 43063-671; 62559-250; 63187-793; 50090-0613; 50090-1789; 42291-404; 42799-111; 80425-0140; 35356-711; 63629-3641; 51672-4018; 70934-282; 63629-1936; 43353-294; 60429-311; 69238-1343; 51672-4053; 60429-243; 50090-4053; 65841-778; 71335-1958; 68788-7300; 80425-0181; 60505-0041; 51672-4036; 80425-0126; 12658-0580; 16714-499; 65841-777; 0093-1122; 60760-298; 51672-4016; 50090-2133; 71205-140; 16714-498; 16714-497; 51672-4017; 50090-1790; 71335-1230; 67296-1271; 69306-020; 17373-1087; 58793-010; 42799-112; 61919-858; 0185-0675; 67628-1001; 0093-7172; 60505-0102; 76385-119
Synonyms Etodolac | Etodolic Acid | Etodolac, (+-)-Isomer | Etodolac, (-)-Isomer | Etodolac, (S)-Isomer | Ultradol | Etodolac, Monosodium Salt, (+-) Isomer | Etodolac, Monosodium Salt, (S)-Isomer | Lodine | Ramodar | AY-24,236 | AY 24,236 | AY-24236 | AY 24236 | Etodolac, Monosodium Salt
Chemical Information
Molecular Formula C17H21NO3
CAS Registry Number 41340-25-4
SMILES CCC1=C2C(=CC=C1)C3=C(N2)C(OCC3)(CC)CC(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Musculoskeletal discomfort15.03.04.001--Not Available
Haemorrhage24.07.01.0020.001484%Not Available
Colitis microscopic07.08.01.0110.000989%Not Available
Epidermal necrosis23.03.03.035--Not Available
Urine output increased13.13.03.002--Not Available
Hepatic enzyme increased13.03.01.019--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Gastrointestinal ulcer07.04.04.002--Not Available
Ill-defined disorder08.01.03.049--Not Available
Pulmonary function test decreased13.19.01.001--Not Available
Renal impairment20.01.03.010--Not Available
Cystitis noninfective20.03.02.001--
Oropharyngeal pain22.02.05.022; 07.05.05.0040.001484%
Acute kidney injury20.01.03.0160.001978%
Drug-induced liver injury12.03.01.044; 09.01.07.0230.000516%Not Available
Perforation08.01.03.058--Not Available
The 7th Page    First    Pre   7    Total 7 Pages