Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Emedastine difumarate
Drug ID BADD_D00764
Description Emedastine is an antihistamine used in eye drops to treat allergic conjunctivitis.
Indications and Usage For the temporary relief of the signs and symptoms of allergic conjunctivitis.
Marketing Status Prescription
ATC Code S01GX06
DrugBank ID DB01084
KEGG ID D02249
MeSH ID C043345
PubChem ID 5282485
TTD Drug ID D02XJI
NDC Product Code 0065-0325-05
Brand EMADINE [Alcon Laboratories, Inc.]
Synonym emedastine | emedastine difumarate | 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazole difumarate | KB 2413 | KG 2413 | KG-2413 | KB-2413 | Emadine
Chemical Information
Molecular Formula C25H34N4O9
CAS Registry Number 87233-62-3
SMILES CCOCCN1C2=CC=CC=C2N=C1N3CCCN(CC3)C.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abnormal dreams19.02.03.001; 17.15.02.001--Not Available
Asthenia08.01.01.001--Not Available
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Corneal infiltrates06.08.01.002--Not Available
Dermatitis23.03.04.002--Not Available
Discomfort08.01.08.003--Not Available
Dry eye06.08.02.001--
Dysgeusia17.02.07.003; 07.14.03.001--
Headache17.14.01.001--
Hyperaemia24.03.02.002--Not Available
Keratitis06.04.02.002--
Lacrimation increased06.08.02.004--
Pain08.01.08.004--
Pruritus23.03.12.001--
Rhinitis22.07.03.006; 11.01.13.004--
Sinusitis22.07.03.007; 11.01.13.005--
Vision blurred17.17.01.010; 06.02.06.007--
Vital dye staining cornea present13.07.04.010--Not Available
Sensation of foreign body08.01.09.002--Not Available
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