Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Emedastine
Drug ID BADD_D00763
Description Emedastine is an antihistamine used in eye drops to treat allergic conjunctivitis.
Indications and Usage For the temporary relief of the signs and symptoms of allergic conjunctivitis.
Marketing Status Prescription
ATC Code S01GX06
DrugBank ID DB01084
KEGG ID D07890
MeSH ID C043345
PubChem ID 3219
TTD Drug ID D02XJI
NDC Product Code Not Available
Brand Not Available
Synonym emedastine | emedastine difumarate | 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazole difumarate | KB 2413 | KG 2413 | KG-2413 | KB-2413 | Emadine
Chemical Information
Molecular Formula C17H26N4O
CAS Registry Number 87233-61-2
SMILES CCOCCN1C2=CC=CC=C2N=C1N3CCCN(CC3)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abnormal dreams19.02.03.001; 17.15.02.001--Not Available
Asthenia08.01.01.001--Not Available
Asthenopia06.01.01.002--Not Available
Corneal infiltrates06.08.01.002--Not Available
Dermatitis23.03.04.002--Not Available
Discomfort08.01.08.003--Not Available
Dry eye06.08.02.001--
Dysgeusia17.02.07.003; 07.14.03.001--
Endophthalmitis11.01.06.003; 06.04.05.009--
Eye disorder06.08.03.001--Not Available
Eye irritation06.04.05.003--Not Available
Eye pain06.08.03.002--
Headache17.14.01.001--
Hyperaemia24.03.02.002--Not Available
Keratitis06.04.02.002--
Lacrimation increased06.08.02.004--
Nervous system disorder17.02.10.001--Not Available
Ocular hyperaemia06.04.05.004--Not Available
Pain08.01.08.004--
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Sinus headache22.02.05.023; 17.14.01.002--
Sinusitis22.07.03.007; 11.01.13.005--
Skin disorder23.03.03.007--Not Available
Tachycardia02.03.02.007--Not Available
Vision blurred17.17.01.010; 06.02.06.007--
Vital dye staining cornea present13.07.04.010--Not Available
Foreign body sensation in eyes06.01.01.006--Not Available
Conjunctival hyperaemia06.04.01.004--Not Available
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