Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Efinaconazole
Drug ID BADD_D00750
Description Efinaconazole is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the nail, known as onychomycosis. It was approved for use in Canada and the USA in 2014 and is marketed by Valeant Pharmaceuticals North America LLC under the name Jublia.
Indications and Usage Indicated in the treatment of fungal infection of the nail, known as onychomycosis.
Marketing Status Prescription
ATC Code D01AC19
DrugBank ID DB09040
KEGG ID D10021
MeSH ID C431707
PubChem ID 489181
TTD Drug ID D0G4BI
NDC Product Code 66064-1024; 46438-0644; 51265-541; 0187-5400; 76397-017; 70600-001; 58175-0606; 51686-0012; 76397-018; 51557-001; 76397-006; 65015-896; 46016-1642; 68259-1314; 66039-930
Synonyms efinaconazole | KP 103 | KP103 | KP-103 | Jublia
Chemical Information
Molecular Formula C18H22F2N4O
CAS Registry Number 164650-44-6
SMILES CC(C(CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3CCC(=C)CC3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Application site dermatitis23.03.04.014; 12.07.01.018; 08.02.01.018--Not Available
Application site pain12.07.01.004; 08.02.01.004--Not Available
Application site rash23.03.13.008; 12.07.01.016; 08.02.01.016--Not Available
Ingrowing nail23.02.05.011--Not Available
Instillation site pain12.07.01.008; 08.02.01.008--Not Available
Paronychia23.09.04.001; 11.01.12.001--
Application site vesicles23.03.01.009; 12.07.01.009; 08.02.01.009--Not Available
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