| Drug Name |
Duloxetine |
| Drug ID |
BADD_D00734 |
| Description |
Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686.[A178741] Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder.[L6454] It has since received approval for a variety of indications including the treatment of neuropathic pain, Generalized Anxiety disorder, osteoarthritis, and stress incontinence. Duloxetine continues to be investigated for the treatment of pain in cancer, surgery, and more. |
| Indications and Usage |
Authors unspecified: Duloxetine: new indication. Depression and diabetic neuropathy: too many adverse effects. Prescrire Int. 2006 Oct;15(85):168-72. |
| Marketing Status |
Prescription |
| ATC Code |
N06AX21 |
| DrugBank ID |
DB00476
|
| KEGG ID |
D07880
|
| MeSH ID |
D000068736
|
| PubChem ID |
60835
|
| TTD Drug ID |
D01AXB
|
| NDC Product Code |
55700-605; 60760-461; 53002-1561; 50436-0198; 71610-403; 47335-383; 70518-3287; 71205-005; 0228-2890; 43547-381; 61919-422; 53002-1494; 71205-358; 46708-279; 70710-1539; 68788-7672; 43547-379; 63629-5174; 80425-0119; 47335-616; 70710-1537; 55154-4981; 68180-294; 65841-801; 55154-4980; 45865-816; 70518-1128; 46708-278; 46708-280; 63629-8748; 47335-382; 70710-1538; 49252-007; 68382-386; 71205-602; 70771-1345; 68084-692; 61919-483; 50090-4011; 50090-4709; 51655-237; 67877-263; 47335-618; 71205-445; 70771-1344; 68382-387; 71335-2017; 68788-7935; 27241-099; 50268-288; 68180-296; 65841-799; 71335-1672; 70518-1011; 31722-168; 0228-2892; 63629-5202; 67877-265; 68180-295; 27241-164; 65977-0035; 47335-381; 70518-1054; 60760-462; 50090-5940; 47335-619; 68382-385; 31722-169; 50268-287; 45865-813; 68084-683; 63629-8051; 70771-1346; 65841-800; 43547-380; 49252-008; 71205-525; 68071-4700; 50090-4708; 55700-628; 70518-2855; 68180-297; 47335-617; 70518-3177; 31722-581; 70518-1139; 31722-582; 27241-098; 49252-009; 27241-097; 55700-727; 71335-0402; 67877-264; 68788-7828; 31722-583; 71335-1964; 68084-675; 0228-2891; 50436-0199; 50268-286; 31722-170; 70518-2630 |
| Synonyms |
Duloxetine Hydrochloride | Hydrochloride, Duloxetine | Duloxetine HCl | HCl, Duloxetine | LY 248686 | LY-248686 | LY248686 | Duloxetine Ethanedioate (1:1), (+-)-isomer - T353987 | LY 227942 | LY-227942 | LY227942 | Duloxetine | N-methyl-3-(1-naphthalenyloxy)-3-(2-thiophene)propanamide | N-methyl-3-(1-naphthalenyloxy)-2-thiophenepropanamine | Duloxetine, (+)-isomer | Cymbalta |
