| Pharmaceutical Information |
| Drug Name |
Dinoprost tromethamine |
| Drug ID |
BADD_D00683 |
| Description |
The tromethamine (THAM) salt of the naturally occurring prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline powder. Dinoprost tromethamine may also be known as dinoprost trometamol, PGF2 alpha THAM, or prostaglandin F2 alpha tromethamine. |
| Indications and Usage |
Used for aborting second-trimester pregnancy (between the twelfth to eighteenth week of gestation) and in incomplete abortion or for therapeutic abortion in cases of intrauterine fetal death and congenital abnormalities incompatible with life. Also used at low-doses for medically indicated induction of labor at term. Also injected intra-arterially for use as a vasodilator to assist in angiography. |
| Marketing Status |
Discontinued |
| ATC Code |
G02AD01 |
| DrugBank ID |
DB01160
|
| KEGG ID |
D01352
|
| MeSH ID |
C010714
|
| PubChem ID |
5282415
|
| TTD Drug ID |
D04RGA
|
| NDC Product Code |
0009-5031; 69870-088 |
| Synonyms |
dinoprost tromethamine | PGF2alpha tromethamine | prostaglandin F2alpha tromethamine | Lutalyse | Minprostin F2 Alpha | Prostin F2 | Prostin F2 Alpha |
|
| Chemical Information |
| Molecular Formula |
C24H45NO8 |
| CAS Registry Number |
38562-01-5 |
| SMILES |
CCCCCC(C=CC1C(CC(C1CC=CCCCC(=O)O)O)O)O.C(C(CO)(CO)N)O |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Miosis | Vasopressin V1a receptor | P37288 | T79232 | Not Available |
|
| ADRs Induced by Drug |
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|
