Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Uterine rupture
ADR ID BADD_A04492
ADR Hierarchy
12      Injury, poisoning and procedural complications
12.01      Injuries NEC
12.01.15      Reproductive system and breast injuries
12.01.15.001      Uterine rupture
18      Pregnancy, puerperium and perinatal conditions
18.02      Maternal complications of pregnancy
18.02.02      Maternal complications of pregnancy NEC
18.02.02.001      Uterine rupture
21      Reproductive system and breast disorders
21.07      Uterine, pelvic and broad ligament disorders
21.07.01      Uterine disorders NEC
21.07.01.009      Uterine rupture
Description A complete separation or tear in the wall of the UTERUS with or without expulsion of the FETUS. It may be due to injuries, multiple pregnancies, large fetus, previous scarring, or obstruction. [MeSH]
MedDRA Code 10046820
MeSH ID D014597
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Rupture of uterus before onset of labor | Rupture of uterus before onset of labor, antepartum | Rupture of uterus before onset of labor, unspecified as to episode of care | Rupture of uterus before onset of labor, with delivery | Rupture of uterus before onset of labour | Rupture of uterus during and after labor | Rupture of uterus during and after labour | Rupture of uterus during labor, delivered, with mention of postpartum complication | Rupture of uterus during labor, delivered, with or without mention of antepartum condition | Rupture of uterus during labor, postpartum condition or complication | Rupture of uterus during labor, unspecified as to episode of care or not applicable | Rupture uterus | Ruptured uterus | Ruptured uterus (labour complication) | Uterine rupture | Uterus rupture | Uterus ruptured | Ruptured uterus (labor complication) | Rupture of uterus before onset of labour, with delivery | Uterine Rupture | Rupture, Uterine | Ruptures, Uterine | Uterine Ruptures
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00365Carboprost--
BADD_D00366Carboprost tromethamine--
BADD_D00682Dinoprost--
BADD_D00683Dinoprost tromethamine--
BADD_D00684Dinoprostone0.001023%
BADD_D01107Hydroxyprogesterone caproate-
BADD_D01281Levonorgestrel0.004169%
BADD_D01418Methotrexate0.000560%
BADD_D01463Mifepristone--
BADD_D01477Misoprostol0.025431%
BADD_D01652Oxytocin--
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