| Pharmaceutical Information |
| Drug Name |
Dimethicone |
| Drug ID |
BADD_D00679 |
| Description |
Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care products such as shampoo, conditioner, leave-in conditioner, and de-tangling products. On skin, it is also observed to have moisturizing actions [L1771, L1773].
A study found that that the 100 % dimethicone product is a safe and highly effective head lice treatment for children and may serve as less toxic and less resistance-prone alternative to pesticide-containing products [L1767]. |
| Indications and Usage |
Dimethicone is a colorless liquid with both cosmetic and therapeutic uses. It is used in topical creams and ointments to help distribute the active ingredients. Dimethicone is used as an anti-foaming agent, a hair and skin conditioner, and in the treatment of head lice and, as an anti-bloating/anti-flatulence agent [L1765], [L1772]. |
| Marketing Status |
Not Available |
| ATC Code |
P03AX05 |
| DrugBank ID |
DB11074
|
| KEGG ID |
D01540
|
| MeSH ID |
C501844
|
| PubChem ID |
24764
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
62654-142; 70567-040; 49035-619; 10742-7006; 64942-1305; 69072-070; 49967-190; 0869-0354; 58503-166; 33992-0057; 60565-016; 53329-021; 60565-012; 0869-0496; 69740-322; 82301-004; 57337-054; 58503-114; 72211-011; 17518-030; 39765-008; 60565-060; 44331-3751; 69968-0408; 64728-032; 64728-030; 59088-333; 69968-0440; 69968-0593; 13630-0114; 36800-785; 53329-059; 71521-395; 71141-619; 66977-022; 58503-107; 57337-098; 37808-995; 82160-351; 64728-033; 64942-1307; 58503-118; 24385-619; 69072-030; 69153-100; 69968-0629; 71080-0028; 10888-8173; 60716-070; 58503-054; 69968-0441; 36800-619; 59608-005; 69072-040; 36800-324; 30142-619; 53329-078; 11770-2120; 57337-100; 69570-202; 0259-2202; 62654-146; 71121-010; 60565-010; 42669-099; 69881-003; 63940-074; 64728-031; 64024-619; 70567-070; 71358-852; 71521-392; 73302-204; 42669-112; 71810-101; 70557-002; 53329-775; 0132-0326; 81310-010; 55910-354; 49035-575; 53329-075; 11822-3221; 69740-044; 60565-030; 60565-020; 58892-105; 69968-0632; 43689-0024; 0299-4114; 33992-3035; 57337-055; 69072-080; 53462-915; 55316-009; 76184-0102; 70567-060; 0187-1660; 63148-028; 64487-3624; 73302-203; 69968-0432; 55319-514; 63148-319; 0869-0619; 53329-157; 71444-789; 58503-167; 58503-055; 11770-2124; 82301-001; 57337-139; 0363-2247; 11701-063; 72211-010; 53329-160; 49967-805; 69968-0437; 69968-0454; 10742-7002; 68437-014; 57337-038; 69072-100; 71358-014; 10742-7005; 50484-044; 69968-0428; 80695-101; 0132-8744; 41250-985; 69842-771; 41190-619; 63148-006; 10742-7003; 70441-0004; 60565-017; 0093-3204; 60565-014; 11701-047; 59779-749; 57337-037; 59608-009; 72476-619; 59608-006; 49967-744; 69968-0680; 10742-7008; 49035-496; 71358-011; 63148-561; 69968-0631; 21130-898; 43553-0001; 49035-062; 58503-070; 68437-013; 58503-038; 69072-060; 69968-0488; 53329-152; 76184-0101; 33992-0058; 76184-0100; 71574-500; 71358-849; 68828-704; 68998-201; 0299-4115; 33992-0054; 61301-8009; 11770-2125; 63736-031; 11770-2121; 69072-090; 69968-0656; 64487-3623; 20276-044; 71080-0029; 10742-7007; 68998-200; 70441-0003; 53329-776; 63517-126; 60565-013; 62654-144; 68828-445; 63517-125; 76176-063; 63148-563; 69570-102; 49967-925; 57337-138; 10888-8152; 59088-829; 69968-0692; 58503-037; 69968-0417; 53329-151; 69968-0679; 72288-496; 63517-131; 70567-030; 68599-0204; 69968-0630; 76470-012; 0259-2102; 69968-0236; 69072-050; 33992-0055; 61301-8005; 41163-750; 53329-143; 53329-777; 70567-050; 72288-619; 56062-619; 53329-142; 13630-0232; 64487-3640; 46783-004; 11770-2123; 11701-062; 53329-161; 53329-074; 81310-009; 67751-183; 71975-010; 69968-0350; 59078-150; 81647-100; 69968-0592; 71732-010; 63517-121; 53329-140; 11770-2122; 10967-675; 55301-619; 71358-850; 71080-0025; 24385-118; 10742-8508; 63517-122 |
| Synonyms |
dimethicone | dimeticone | dimethyl polysiloxane |
|
| Chemical Information |
| Molecular Formula |
C6H18OSi2 |
| CAS Registry Number |
107-46-0 |
| SMILES |
C[Si](C)(C)O[Si](C)(C)C |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
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