Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Diethylpropion hydrochloride
Drug ID BADD_D00663
Description A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Indications and Usage Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Marketing Status Prescription; Discontinued
ATC Code A08AA03
DrugBank ID DB00937
KEGG ID D03801
MeSH ID D004053
PubChem ID 91442
TTD Drug ID D0B7OD
NDC Product Code 10920-600; 17337-0016; 71335-0049; 63629-8215; 50090-0327; 63187-947; 10702-044; 38779-0926; 43063-532; 0527-1475; 63187-621; 50090-0120; 12634-530; 71335-1779; 0527-1477; 72789-117; 71335-0175; 43063-348
Synonyms Diethylpropion | Amfepramon | Amfepramone | Phepranon | 2-Diethylaminopropiophenone | Anorex | Lipomin | Regenon | Dietil-retard | Dietil retard | Dietilretard | Regibon | Tenuate | Delgamer | Maruate | Modératan | Neobes | Nobesine | Propion | Préfamone | Tepanil | Diethylpropion Hydrochloride | Hydrochloride, Diethylpropion | Ifa Norex | Norex, Ifa
Chemical Information
Molecular Formula C13H20ClNO
CAS Registry Number 134-80-5
SMILES CCN(CC)C(C)C(=O)C1=CC=CC=C1.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Menstrual disorder21.01.01.004--Not Available
Myalgia15.05.02.001--
Mydriasis17.02.11.003; 06.05.03.004--Not Available
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Palpitations02.01.02.003--
Polyuria20.02.03.002--Not Available
Pulmonary hypertension24.08.03.002; 22.06.01.001--
Rash23.03.13.001--Not Available
Restlessness19.11.02.002; 17.02.05.021--
Seizure17.12.03.001--
Somnolence19.02.05.003; 17.02.04.006--
Tachycardia02.03.02.007--Not Available
Tremor17.01.06.002--
Urticaria23.04.02.001; 10.01.06.001--
Ventricular arrhythmia02.03.04.006--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
Electrocardiogram change13.14.05.014--Not Available
Libido disorder21.03.02.006; 19.08.03.004--Not Available
Cardiac valve disease02.07.02.001--Not Available
Erectile dysfunction21.03.01.007; 19.08.04.001--
Psychotic disorder19.03.01.002--
Bone marrow failure01.03.03.005--
Device stimulation issue27.01.02.005--Not Available
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