Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Diethylpropion
Drug ID BADD_D00662
Description A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Indications and Usage Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Marketing Status Prescription; Discontinued
ATC Code A08AA03
DrugBank ID DB00937
KEGG ID D07444
MeSH ID D004053
PubChem ID 7029
TTD Drug ID D0B7OD
NDC Product Code Not Available
Synonyms Diethylpropion | Amfepramon | Amfepramone | Phepranon | 2-Diethylaminopropiophenone | Anorex | Lipomin | Regenon | Dietil-retard | Dietil retard | Dietilretard | Regibon | Tenuate | Delgamer | Maruate | Modératan | Neobes | Nobesine | Propion | Préfamone | Tepanil | Diethylpropion Hydrochloride | Hydrochloride, Diethylpropion | Ifa Norex | Norex, Ifa
Chemical Information
Molecular Formula C13H19NO
CAS Registry Number 90-84-6
SMILES CCN(CC)C(C)C(=O)C1=CC=CC=C1
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hyperhidrosis23.02.03.004; 08.01.03.028--
Insomnia19.02.01.002; 17.15.03.002--
Leukopenia01.02.02.001--Not Available
Malaise08.01.01.003--
Myalgia15.05.02.001--
Mydriasis17.02.11.003; 06.05.03.004--Not Available
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Palpitations02.01.02.003--
Pancytopenia01.03.03.003--Not Available
Polyuria20.02.03.002--Not Available
Pulmonary hypertension24.08.03.002; 22.06.01.001--
Rash23.03.13.001--Not Available
Seizure17.12.03.001--
Somnolence19.02.05.003; 17.02.04.006--
Tachycardia02.03.02.007--Not Available
Tension19.06.02.005--Not Available
Tremor17.01.06.002--
Urticaria23.04.02.001; 10.01.06.001--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
Emotional distress19.04.02.008--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Urine output increased13.13.03.002--Not Available
Electrocardiogram change13.14.05.014--Not Available
Cardiac valve disease02.07.02.001--Not Available
Erectile dysfunction21.03.01.007; 19.08.04.001--
Ill-defined disorder08.01.03.049--Not Available
Psychotic disorder19.03.01.002--
Pulmonary arterial hypertension22.06.01.002; 24.08.03.003--Not Available
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