Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Diethylpropion
Drug ID BADD_D00662
Description A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Indications and Usage Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Marketing Status Prescription; Discontinued
ATC Code A08AA03
DrugBank ID DB00937
KEGG ID D07444
MeSH ID D004053
PubChem ID 7029
TTD Drug ID D0B7OD
NDC Product Code Not Available
Synonyms Diethylpropion | Amfepramon | Amfepramone | Phepranon | 2-Diethylaminopropiophenone | Anorex | Lipomin | Regenon | Dietil-retard | Dietil retard | Dietilretard | Regibon | Tenuate | Delgamer | Maruate | Modératan | Neobes | Nobesine | Propion | Préfamone | Tepanil | Diethylpropion Hydrochloride | Hydrochloride, Diethylpropion | Ifa Norex | Norex, Ifa
Chemical Information
Molecular Formula C13H19NO
CAS Registry Number 90-84-6
SMILES CCN(CC)C(C)C(=O)C1=CC=CC=C1
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Agranulocytosis01.02.03.001--Not Available
Alopecia23.02.02.001--
Anxiety19.06.02.002--
Arrhythmia02.03.02.001--Not Available
Blood pressure increased13.14.03.005--Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Constipation07.02.02.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Dyskinesia17.01.02.006--
Dysmenorrhoea21.01.01.002--
Dyspepsia07.01.02.001--
Dysphoria19.04.02.004--Not Available
Dyspnoea22.02.01.004; 02.01.03.002--
Dysuria20.02.02.002--
Ecchymosis23.06.01.001; 24.07.06.002; 01.01.03.001--Not Available
Epilepsy17.12.03.002--Not Available
Erythema23.03.06.001--Not Available
Euphoric mood19.04.02.006--
Feeling abnormal08.01.09.014--Not Available
Feeling jittery08.01.09.016--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gynaecomastia21.05.04.003; 05.05.02.003--
Headache17.14.01.001--
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