Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Diazoxide
Drug ID BADD_D00649
Description A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
Indications and Usage Used parentally to treat hypertensive emergencies. Also used to treat hypoglycemia secondary to insulinoma.
Marketing Status Prescription; Discontinued
ATC Code C02DA01; V03AH01
DrugBank ID DB01119
KEGG ID D00294
MeSH ID D003981
PubChem ID 3019
TTD Drug ID D07WEP
NDC Product Code 38779-0324; 0575-6200; 58159-039; 52952-003; 69575-4025; 62991-2857; 49452-2541; 51927-2742; 38779-3184; 71052-664; 0254-1010; 13517-100; 14501-0096; 45562-1740; 51552-1582
Synonyms Diazoxide | Proglycem | Hyperstat
Chemical Information
Molecular Formula C8H7ClN2O2S
CAS Registry Number 364-98-7
SMILES CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Death08.04.01.001--
Dermatitis23.03.04.002--Not Available
Diabetic hyperosmolar coma05.07.04.001; 17.02.09.003; 14.07.04.001--Not Available
Diabetic ketoacidosis14.07.03.001; 05.07.03.001--Not Available
Diarrhoea07.02.01.001--
Diplopia17.17.01.005; 06.02.06.002--Not Available
Discomfort08.01.08.003--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Drug interaction08.06.03.001--Not Available
Dry mouth07.06.01.002--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspnoea02.01.03.002; 22.02.01.004--
Electrocardiogram abnormal13.14.05.001--Not Available
Eosinophilia01.02.04.001--
Epilepsy17.12.03.0020.000969%Not Available
Euphoric mood19.04.02.006--
Extrapyramidal disorder17.01.02.007--
Febrile convulsion08.05.02.009; 17.12.03.0040.000646%Not Available
Feeling abnormal08.01.09.014--Not Available
Feeling hot08.01.09.009--Not Available
Fluid retention20.01.02.003; 14.05.06.002--Not Available
Flushing08.01.03.025; 24.03.01.002; 23.06.05.003--
Galactorrhoea21.05.02.002; 05.03.04.002--Not Available
Gastroenteritis11.01.07.004; 07.19.03.0010.000646%Not Available
Gastrointestinal pain07.01.05.005--
Glycosuria20.02.01.005--
Gout15.01.06.001; 14.09.01.001--Not Available
Haematuria24.07.01.047; 20.02.01.006--
Haemoglobin13.01.05.018--Not Available
Haemoglobin decreased13.01.05.003--Not Available
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