| Drug Name |
Diazepam |
| Drug ID |
BADD_D00648 |
| Description |
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome. (From Martindale, The Extra Pharmacopoeia, 30th ed, p589)
Given diazepam's storied history as a commonly used and effective medication for a variety of indications, contemporary advancements in the formulation and administration of the agent include the development and US FDA approval of an auto-injectable formulation for the rapid treatment of uncontrolled seizures in 2015-2016 [L5200]. Combining diazepam, a proven effective therapy for acute repetitive seizures, with an auto-injector designed for subcutaneous administration that is quickly and easily administered offers the potential for complete, consistent drug absorption and rapid onset of effect [L5200]. This current development is subsequently an important addition to the rescue therapy tool chest for patients with epilepsy [L5200]. |
| Indications and Usage |
Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
N05BA01 |
| DrugBank ID |
DB00829
|
| KEGG ID |
D00293
|
| MeSH ID |
D003975
|
| PubChem ID |
3016
|
| TTD Drug ID |
D07JVL
|
| NDC Product Code |
0904-7117; 43063-970; 80425-0151; 70518-0162; 71872-7259; 52584-213; 68071-3330; 70518-1856; 70518-1270; 51862-943; 11014-0401; 68071-4899; 51862-942; 51862-941; 69339-136; 71610-427; 80425-0120; 71872-7260; 0140-0005; 69339-137; 67544-019; 0527-1767; 50090-3390; 0615-7800; 35356-812; 43353-278; 0378-0477; 61919-409; 11014-0400; 66490-650; 43353-281; 51079-286; 71554-118; 49452-2538; 63187-867; 68682-650; 67296-0291; 0409-1273; 71335-0444; 71610-460; 67296-0084; 12828-0013; 52584-273; 50090-4566; 45865-423; 63187-173; 58118-0640; 71610-424; 60760-934; 0527-1768; 0409-3213; 70518-2358; 0395-8143; 71610-270; 72252-510; 11014-0399; 55154-5074; 45865-482; 50090-1726; 68788-7452; 43353-825; 61919-906; 64330-010; 68071-4181; 51079-284; 0378-0345; 71610-459; 58118-4047; 61919-071; 68682-655; 68071-4770; 38779-0925; 63187-544; 68071-4829; 50090-0195; 0187-0659; 50090-2249; 45865-140; 11704-600; 71335-1584; 0378-0271; 48087-0005; 51927-0051; 72189-193; 0054-3188; 0641-6244; 63187-846; 53002-3340; 72252-520; 51552-1025; 0140-0006; 0140-0004; 58118-3926; 55289-092; 0172-3926; 70518-1713; 50090-1913; 0615-7799; 68682-652; 0121-0905; 63739-073; 80725-006; 63629-1523; 72252-515; 58118-3925; 43063-840; 55700-058; 51927-1014; 72252-505; 63629-2948; 60760-927; 43063-718; 48087-0112; 67544-020; 80725-004; 0172-3927; 55154-7885; 68071-3270; 0904-5880; 68071-4922; 80725-005; 0404-9848; 0187-0658; 50090-4713; 72572-140; 63629-7328; 49999-018; 68788-9207; 43063-987; 43353-276; 51079-285; 68094-750; 0172-3925; 70518-0014 |
| Synonyms |
Diazepam | 7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one | Diazemuls | Faustan | Valium | Seduxen | Sibazon | Stesolid | Apaurin | Relanium |
