Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dextroamphetamine
Drug ID BADD_D00636
Description Dextroamphetamine is the dextrorotary enantiomer of amphetamine[A2505]. Dextroamphetamine was approved by the FDA in 2001 for the treatment of attention deficit hyperactivity disorder[L6010,Label].
Indications and Usage Used to treat attention deficit hyperactivity disorder (ADHD).
Marketing Status Prescription; Discontinued
ATC Code N06BA02
DrugBank ID DB01576
KEGG ID D03740
MeSH ID D003913
PubChem ID 5826
TTD Drug ID D0T3LF
NDC Product Code 27808-085
Synonyms Dextroamphetamine | Dexamphetamine | Dexamfetamine | dextro-Amphetamine | dextro Amphetamine | d-Amphetamine | d Amphetamine | Dexedrine | DextroStat | Oxydess | Curban | Dextroamphetamine Sulfate | Sulfate, Dextroamphetamine | Dextro-Amphetamine Sulfate | Dextro Amphetamine Sulfate | d-Amphetamine Sulfate | d Amphetamine Sulfate
Chemical Information
Molecular Formula C9H13N
CAS Registry Number 51-64-9
SMILES CC(CC1=CC=CC=C1)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypotension24.06.03.0020.001737%
Increased appetite14.03.01.003; 08.01.09.0270.001737%Not Available
Insomnia19.02.01.002; 17.15.03.0020.003473%
Intentional self-injury19.12.01.002; 12.01.08.0360.001737%Not Available
Metabolic acidosis14.01.01.0030.003473%Not Available
Myocardial ischaemia02.02.02.008; 24.04.04.0100.000680%Not Available
Nausea07.01.07.0010.005210%
Nightmare19.02.03.0030.001737%Not Available
Palpitations02.01.02.003--
Paraesthesia17.02.06.0050.001737%
Rash23.03.13.0010.002605%Not Available
Respiratory depression22.02.01.010; 17.02.05.0470.001737%Not Available
Restlessness19.11.02.002; 17.02.05.021--
Rhabdomyolysis15.05.05.0020.004342%
Seizure17.12.03.0010.001737%
Somnolence19.02.05.003; 17.02.04.0060.003473%
Tachycardia02.03.02.0070.000680%Not Available
Thrombocytopenia01.08.01.0020.001737%Not Available
Tic19.11.04.001; 17.02.05.024--Not Available
Tourette's disorder19.11.04.002; 17.19.02.001; 03.10.01.001--Not Available
Tremor17.01.06.002--
Urinary hesitation20.02.02.0090.001737%Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vertigo17.02.12.002; 04.04.01.0030.001737%
Vomiting07.01.07.0030.003473%
Weight decreased13.15.01.0050.001737%
Libido disorder21.03.02.006; 19.08.03.004--Not Available
Ischaemic stroke24.04.06.010; 17.08.01.0180.003473%Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Erectile dysfunction21.03.01.007; 19.08.04.001--
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