Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dexmedetomidine hydrochloride
Drug ID BADD_D00630
Description An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Indications and Usage For sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting, also used in pain relief; anxiety reduction and analgesia
Marketing Status Prescription
ATC Code N05CM18
DrugBank ID DB00633
KEGG ID D01205
MeSH ID D020927
PubChem ID 6918081
TTD Drug ID D0U3DU
NDC Product Code 63323-421; 0143-9525; 43598-976; 68083-239; 12780-4640; 56087-0002; 70771-1319; 71225-132; 68083-238; 52952-006; 0404-9938; 43598-975; 56087-0001; 44567-600; 67457-925; 44567-601; 68382-124; 71872-7030; 42023-187; 67457-924; 0338-9557; 71872-7122; 72572-128; 52584-638; 66794-235; 0409-1174; 68094-247; 51224-015; 44567-602; 0409-3301; 0409-1638; 42023-146; 68094-047; 71225-126; 0409-1434; 68094-147; 57664-596; 71872-7031; 44567-603; 17478-055; 50711-0008; 51224-215; 72572-127; 0143-9526; 50384-0100; 63323-671; 66794-234; 42023-186; 0409-1660; 70121-1388; 51224-115; 57884-0024; 71225-133; 0338-9555; 72015-001; 66583-0510; 70121-1389
Synonyms Dexmedetomidine | MPV-1440 | MPV 1440 | MPV1440 | Precedex | Dexmedetomidine Hydrochloride | Hydrochloride, Dexmedetomidine
Chemical Information
Molecular Formula C13H17ClN2
CAS Registry Number 145108-58-3
SMILES CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pleural effusion22.05.02.002--
Pulmonary congestion24.03.08.001; 22.01.03.002; 02.05.02.002--Not Available
Pulmonary oedema22.01.03.003; 02.05.02.003--
Pyrexia08.05.02.003--
Respiratory depression22.02.01.010; 17.02.05.047--Not Available
Respiratory failure22.02.06.002; 14.01.04.003--
Seizure17.12.03.001--
Sinus tachycardia02.03.03.010--
Speech disorder17.02.08.003; 22.02.05.034; 19.19.02.002--Not Available
Systolic hypertension24.08.02.007--Not Available
Tachycardia02.03.02.007--Not Available
Thirst14.03.02.007; 08.01.09.021--Not Available
Ventricular arrhythmia02.03.04.006--
Ventricular tachycardia02.03.04.010--
Visual impairment06.02.06.008--Not Available
Vomiting07.01.07.003--
Wheezing22.03.01.009--
Post procedural haemorrhage24.07.01.014; 12.02.05.004--
Haemorrhage24.07.01.002--Not Available
Urine output decreased13.13.03.001--
Cardiac disorder02.01.01.003--Not Available
Supraventricular tachyarrhythmia02.03.03.014--Not Available
Acute kidney injury20.01.03.016--
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