Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dexmedetomidine
Drug ID BADD_D00629
Description An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Indications and Usage For sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting, also used in pain relief; anxiety reduction and analgesia
Marketing Status Prescription
ATC Code N05CM18
DrugBank ID DB00633
KEGG ID D00514
MeSH ID D020927
PubChem ID 5311068
TTD Drug ID D0U3DU
NDC Product Code 55150-209; 66794-230; 70860-605; 62068-308; 71872-7150; 66794-238; 66794-233; 16729-432; 71288-505; 67457-251; 16729-239
Synonyms Dexmedetomidine | MPV-1440 | MPV 1440 | MPV1440 | Precedex | Dexmedetomidine Hydrochloride | Hydrochloride, Dexmedetomidine
Chemical Information
Molecular Formula C13H16N2
CAS Registry Number 113775-47-6
SMILES CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cardiopulmonary failure22.02.06.004; 02.05.01.0040.000157%Not Available
Acute coronary syndrome24.04.04.011; 02.02.02.015--Not Available
Gastrointestinal hypomotility07.02.02.0050.000903%Not Available
Respiratory tract congestion22.02.07.003--Not Available
Haemorrhage24.07.01.002--Not Available
Cerebrovascular insufficiency24.04.06.004; 17.08.02.0030.000602%Not Available
Angiopathy24.03.02.007--Not Available
Blood alkaline phosphatase increased13.04.02.004--
Cardiac disorder02.01.01.003--Not Available
Infarction24.04.02.017--Not Available
Malnutrition14.03.02.004--Not Available
Mediastinal disorder22.09.03.001--Not Available
Mental disorder19.07.01.002--Not Available
Red blood cell abnormality01.07.02.006--Not Available
Obstructive airways disorder22.03.01.0110.001806%Not Available
Pulmonary function test decreased13.19.01.001--Not Available
Unevaluable event08.01.03.0510.000602%Not Available
Upper airway obstruction22.02.05.0290.004214%Not Available
Acute kidney injury20.01.03.016--
Sinus node dysfunction02.03.03.0170.000602%
Neonatal hypotension24.06.03.014; 18.04.07.0080.001505%Not Available
Lymphocyte percentage increased13.01.06.0550.000903%Not Available
Abdominal compartment syndrome24.04.09.009; 07.11.01.0170.000602%Not Available
Glossoptosis07.14.02.018; 22.02.08.0180.000602%Not Available
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