Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Delavirdine mesylate
Drug ID BADD_D00604
Description A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.
Indications and Usage For the treatment of HIV-1 infection in combination with appropriate antiretroviral agents when therapy is warranted
Marketing Status Prescription
ATC Code J05AG02
DrugBank ID DB00705
KEGG ID D00895
MeSH ID D020008
PubChem ID 441386
TTD Drug ID D0G6SD
NDC Product Code Not Available
Synonyms Delavirdine | Rescriptor | U-90152 | U 90152 | U90152 | U-90152S | U 90152S | U90152S | Delavirdine Mesylate | Mesylate, Delavirdine
Chemical Information
Molecular Formula C23H32N6O6S2
CAS Registry Number 147221-93-0
SMILES CC(C)NC1=C(N=CC=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)NS(=O)(=O)C.CS(=O)(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Tongue ulceration07.14.01.003--Not Available
Tooth abscess11.01.04.003; 07.09.01.003--Not Available
Toothache07.09.06.001--
Tremor17.01.06.002--
Tuberculosis11.04.01.006--Not Available
Upper respiratory tract infection11.01.13.009; 22.07.03.011--
Urinary tract infection20.08.02.001; 11.01.14.004--
Urticaria23.04.02.001; 10.01.06.001--
Vertigo17.02.12.002; 04.04.01.003--
Viral infection11.05.04.001--Not Available
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
Weight decreased13.15.01.005--
Weight increased13.15.01.006--
Fat redistribution14.08.04.002--Not Available
Localised oedema08.01.07.011; 02.05.04.006; 14.05.06.009--
Contusion24.07.06.001; 23.03.11.002; 15.03.01.008; 12.01.06.001--
Respiratory tract congestion22.02.07.003--Not Available
Affect lability19.04.01.001--Not Available
Body fat disorder14.08.04.012--Not Available
Cognitive disorder19.21.02.001; 17.03.03.003--
Nuchal rigidity17.05.02.006; 15.05.04.005--Not Available
Blood alkaline phosphatase increased13.04.02.004--
Decreased appetite08.01.09.028; 14.03.01.005--
Erectile dysfunction21.03.01.007; 19.08.04.001--
Skin mass23.07.04.014--Not Available
Acute kidney injury20.01.03.016--
Anal incontinence17.05.01.021; 07.01.06.029--
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