Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Delavirdine
Drug ID BADD_D00603
Description A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.
Indications and Usage For the treatment of HIV-1 infection in combination with appropriate antiretroviral agents when therapy is warranted
Marketing Status Prescription
ATC Code J05AG02
DrugBank ID DB00705
KEGG ID D07782
MeSH ID D020008
PubChem ID 5625
TTD Drug ID D0G6SD
NDC Product Code Not Available
Synonyms Delavirdine | Rescriptor | U-90152 | U 90152 | U90152 | U-90152S | U 90152S | U90152S | Delavirdine Mesylate | Mesylate, Delavirdine
Chemical Information
Molecular Formula C22H28N6O3S
CAS Registry Number 136817-59-9
SMILES CC(C)NC1=C(N=CC=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)NS(=O)(=O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Rash23.03.13.001--Not Available
Rash maculo-papular23.03.13.004--
Rash pustular23.03.10.003; 11.01.12.002--
Renal pain20.02.03.003--Not Available
Retching07.01.07.002--Not Available
Rhabdomyolysis15.05.05.002--
Rhinitis22.07.03.006; 11.01.13.004--
Salivary hypersecretion07.06.01.009--Not Available
Seborrhoeic dermatitis23.03.04.018--Not Available
Shock24.06.02.002--Not Available
Sialoadenitis11.01.04.002; 07.06.04.002--
Sinusitis22.07.03.007; 11.01.13.005--
Skin disorder23.03.03.007--Not Available
Skin exfoliation23.03.07.003--Not Available
Skin hypertrophy23.01.04.002--Not Available
Skin papilloma23.10.01.002; 16.26.01.002; 11.05.07.001--
Somnolence19.02.05.003; 17.02.04.006--
Spleen disorder01.09.02.003--Not Available
Stevens-Johnson syndrome11.07.01.005; 10.01.03.020; 23.03.01.007; 12.03.01.014--
Stomatitis07.05.06.005--
Swelling08.01.03.015--Not Available
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Tachycardia02.03.02.007--Not Available
Tendon disorder15.07.01.002--Not Available
Tenosynovitis15.07.01.004--Not Available
Tension19.06.02.005--Not Available
Testicular pain21.13.01.005--
Tetany15.05.03.013; 14.04.01.005; 05.04.02.003--Not Available
Thirst14.03.02.007; 08.01.09.021--Not Available
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