Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Deferasirox
Drug ID BADD_D00594
Description Deferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload in patients receiving long term blood transfusions.
Indications and Usage For the treatment of chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients 2 years of age and older.
Marketing Status Prescription
ATC Code V03AC03
DrugBank ID DB01609
KEGG ID D03669
MeSH ID D000077588
PubChem ID 214348
TTD Drug ID D0Q5UQ
NDC Product Code 62332-412; 43598-856; 57664-769; 62332-411; 62756-569; 0078-0469; 70771-1411; 66039-871; 69097-550; 70771-1471; 72647-371; 62512-0078; 68462-494; 69539-021; 31722-012; 69097-391; 57664-770; 58032-2017; 69539-200; 63278-1070; 72647-372; 46708-324; 69452-159; 62332-410; 53104-7713; 72606-014; 11722-040; 69097-570; 43598-851; 62332-324; 67877-549; 69539-022; 66022-0301; 0591-3853; 45963-456; 14501-0049; 46708-410; 62332-325; 46708-879; 72606-013; 62756-570; 69238-1486; 43598-854; 65085-0063; 62332-326; 69238-1704; 70710-1011; 59285-010; 46708-326; 70710-1012; 59651-419; 16714-995; 69539-199; 72205-076; 65727-037; 74436-0323; 57664-768; 68462-495; 46708-325; 69452-160; 0078-0713; 65015-738; 16714-993; 69097-393; 69097-560; 0078-0470; 31722-013; 69539-074; 43598-853; 70700-269; 70771-1409; 49706-2103; 70710-1277; 43598-855; 0078-0468; 65372-1164; 16714-994; 43598-852; 45963-455; 46708-412; 0078-0727; 70771-1472; 72647-373; 68462-496; 67877-553; 69238-1703; 45963-454; 69452-161; 0078-0654; 62756-568; 70771-1473; 69539-023; 67877-550; 0078-0720; 70710-1275; 31722-011; 72606-015; 70771-1410; 69539-075; 67877-551; 70710-1013; 67877-554; 72205-075; 0078-0656; 70700-270; 69238-1702; 0078-0655; 46708-411; 69097-392; 69539-073; 69238-1487; 67877-552; 70700-271; 70710-1276; 69238-1488
Synonyms Deferasirox | 4-(3,5-Bis-(2-hydroxyphenyl)-(1,2,4)-triazol-1-yl)benzoic acid | ICL 670A | ICL-670A | ICL670A | ICL-670 | ICL670 | ICL 670 | Exjade
Chemical Information
Molecular Formula C21H15N3O4
CAS Registry Number 201530-41-8
SMILES C1=CC=C(C(=C1)C2=NN(C(=N2)C3=CC=CC=C3O)C4=CC=C(C=C4)C(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hepatic function abnormal09.01.02.0010.052481%Not Available
Hepatic pain09.01.05.0050.014578%
Hepatitis09.01.07.0040.032071%Not Available
Hepatitis B11.05.06.002; 09.01.09.0030.005831%
Hepatitis C11.05.06.004; 09.01.09.0050.014578%Not Available
Hepatocellular injury09.01.07.0080.020409%Not Available
Hepatomegaly09.01.05.0010.029156%Not Available
Hepatorenal failure20.01.03.013; 09.01.03.0080.001521%Not Available
Hepatorenal syndrome09.01.03.007; 20.01.03.0120.001521%Not Available
Hepatotoxicity12.03.01.008; 09.01.07.0090.026240%Not Available
Hernia08.01.04.0010.008747%Not Available
Herpes virus infection11.05.02.0080.005831%Not Available
Herpes zoster11.05.02.003; 23.09.03.002--
Hiccups22.02.04.002; 07.01.06.0090.008747%
Hip fracture15.08.03.001; 12.04.01.0010.032071%
HIV infection11.05.17.002; 10.03.03.0020.005831%Not Available
Hydronephrosis20.01.05.0010.005831%Not Available
Hyperammonaemia14.10.01.001; 09.01.02.0020.052481%Not Available
Hyperbilirubinaemia14.11.01.010; 09.01.01.003; 01.06.04.0030.017494%Not Available
Hypercalciuria14.04.01.006; 20.02.01.007; 05.04.01.0030.005831%Not Available
Hyperchloraemia14.05.08.0010.008747%Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hyperkalaemia14.05.03.001--
Hyperkinesia17.01.02.008--Not Available
Hyperpyrexia08.05.02.0020.020409%Not Available
Hypersensitivity10.01.03.003--
Hypersensitivity vasculitis24.05.02.012; 23.06.02.005; 10.02.02.017; 01.01.04.008--Not Available
Hypersomnia19.02.05.001; 17.15.01.001--
Hypersplenism01.09.02.0020.003042%Not Available
The 11th Page    First    Pre   11 12 13 14 15    Next   Last    Total 28 Pages