Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dabigatran
Drug ID BADD_D00563
Description Dabigatran is the active form of the orally bioavailable prodrug [dabigatran etexilate].
Indications and Usage Not Available
Marketing Status approved; investigational
ATC Code B01AE07
DrugBank ID DB14726
KEGG ID D09707
MeSH ID D000069604
PubChem ID 216210
TTD Drug ID D0M7JT
NDC Product Code 51869-0030
UNII I0VM4M70GC
Synonyms Dabigatran | N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine | BIBR 1048 | Pradaxa | Dabigatran Etexilate | Etexilate, Dabigatran | Dabigatran Etexilate Mesylate | Etexilate Mesylate, Dabigatran | Mesylate, Dabigatran Etexilate
Chemical Information
Molecular Formula C25H25N7O3
CAS Registry Number 211914-51-1
SMILES CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Peptic ulcer07.04.07.0010.000905%Not Available
Pericardial effusion02.06.01.0020.019206%
Pericardial haemorrhage24.07.01.013; 02.06.01.0030.010545%Not Available
Pericarditis02.06.02.0010.001884%
Peripheral ischaemia24.04.03.0020.004159%
Petechiae23.06.01.003; 01.01.03.002; 24.07.06.0040.003915%Not Available
Pharyngeal haemorrhage24.07.02.017; 22.04.05.0020.000612%
Pharyngeal ulceration22.04.05.0040.000245%Not Available
Phlebitis24.12.03.004; 12.02.01.0020.002985%
Phlebitis superficial24.12.03.0050.000954%Not Available
Pleural effusion22.05.02.0020.007511%
Pleuritic pain22.12.01.0070.000245%
Pneumothorax22.05.02.0030.003548%
Polymyalgia rheumatica15.06.01.001; 10.04.05.0030.000367%Not Available
Portal vein thrombosis24.01.03.003; 09.01.06.0070.000612%
Proctalgia07.03.02.0010.002031%
Proctitis07.08.04.0010.001615%
Pruritus23.03.12.001--
Pulmonary alveolar haemorrhage22.01.02.005; 24.07.01.0150.002202%Not Available
Pulmonary congestion24.03.08.001; 22.01.03.002; 02.05.02.0020.001101%Not Available
Pulmonary embolism24.01.06.001; 22.06.02.0010.058595%Not Available
Pulmonary haemorrhage22.12.01.009; 24.07.01.0160.007707%
Pulmonary infarction24.04.09.001; 22.06.02.0020.000612%Not Available
Pulmonary oedema22.01.03.003; 02.05.02.0030.004771%
Pupillary disorder17.02.11.006; 06.05.03.0080.000245%Not Available
Quadriplegia17.01.04.0130.000856%Not Available
Rash23.03.13.001--Not Available
Rebound effect08.06.02.0090.000979%Not Available
Rectal cancer16.13.01.003; 07.21.05.0020.001713%Not Available
Rectal haemorrhage24.07.02.018; 07.12.03.0010.054338%
The 9th Page    First    Pre   9 10 11 12 13    Next   Last    Total 22 Pages