Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dabigatran
Drug ID BADD_D00563
Description Dabigatran is the active form of the orally bioavailable prodrug [dabigatran etexilate].
Indications and Usage Not Available
Marketing Status approved; investigational
ATC Code B01AE07
DrugBank ID DB14726
KEGG ID D09707
MeSH ID D000069604
PubChem ID 216210
TTD Drug ID D0M7JT
NDC Product Code 51869-0030
UNII I0VM4M70GC
Synonyms Dabigatran | N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine | BIBR 1048 | Pradaxa | Dabigatran Etexilate | Etexilate, Dabigatran | Dabigatran Etexilate Mesylate | Etexilate Mesylate, Dabigatran | Mesylate, Dabigatran Etexilate
Chemical Information
Molecular Formula C25H25N7O3
CAS Registry Number 211914-51-1
SMILES CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Encephalomalacia17.11.01.0160.000245%Not Available
Small intestinal haemorrhage24.07.02.019; 07.12.03.0020.001101%
Meningorrhagia24.07.04.030; 17.08.01.056; 12.01.10.0160.000856%Not Available
Neurodegenerative disorder17.02.10.0240.000367%Not Available
Cardiac ventricular thrombosis02.11.01.008; 24.01.05.0060.001101%Not Available
Colon cancer metastatic16.13.01.012; 07.21.01.0100.000245%Not Available
Gastrointestinal mucosal disorder07.11.03.0080.000245%Not Available
Palatal oedema07.05.04.0080.000245%Not Available
Peripheral artery occlusion24.04.03.0220.001223%Not Available
Cardiac perforation02.11.01.006; 12.02.01.0200.001101%Not Available
Multi-organ disorder08.01.03.0740.000367%Not Available
Right ventricular dysfunction02.04.02.0330.000367%
Abdominal compartment syndrome24.04.09.009; 07.11.01.0170.000245%Not Available
Thalamus haemorrhage24.07.04.033; 17.08.01.0620.000734%Not Available
Intracranial haematoma24.07.04.027; 17.08.01.0510.001957%Not Available
Embolic cerebral infarction24.01.04.009; 17.08.01.0290.002691%Not Available
Appendix disorder07.11.01.0200.000245%Not Available
Arterial haemorrhage24.07.01.0630.001590%Not Available
Cardiac myxoma16.02.01.006; 02.10.01.0010.000734%Not Available
Cerebellar haematoma24.07.04.022; 17.08.01.0450.000245%Not Available
Gastric mucosal lesion07.11.03.0070.000367%Not Available
Hernia obstructive08.01.04.0030.000367%Not Available
Facial nerve disorder17.04.03.0060.000245%
Aortic valve disease02.07.03.0020.000538%
Angiodysplasia24.03.03.0170.000856%Not Available
Perforated ulcer08.03.06.0020.000367%Not Available
Gallbladder enlargement09.03.02.0050.000245%Not Available
Thoracic haemorrhage22.02.07.017; 24.07.01.0820.000734%Not Available
Basilar artery thrombosis24.01.04.014; 17.08.01.0430.000489%Not Available
Renal embolism24.01.11.003; 20.01.07.0140.000612%Not Available
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