Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dabigatran
Drug ID BADD_D00563
Description Dabigatran is the active form of the orally bioavailable prodrug [dabigatran etexilate].
Indications and Usage Not Available
Marketing Status approved; investigational
ATC Code B01AE07
DrugBank ID DB14726
KEGG ID D09707
MeSH ID D000069604
PubChem ID 216210
TTD Drug ID D0M7JT
NDC Product Code 51869-0030
UNII I0VM4M70GC
Synonyms Dabigatran | N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine | BIBR 1048 | Pradaxa | Dabigatran Etexilate | Etexilate, Dabigatran | Dabigatran Etexilate Mesylate | Etexilate Mesylate, Dabigatran | Mesylate, Dabigatran Etexilate
Chemical Information
Molecular Formula C25H25N7O3
CAS Registry Number 211914-51-1
SMILES CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Metastatic neoplasm16.16.01.0070.000734%Not Available
Motor dysfunction17.01.02.031; 15.05.06.0060.000734%Not Available
Mucosal haemorrhage24.07.01.011; 08.01.06.0050.001982%Not Available
Oesophageal disorder07.11.02.0010.001370%Not Available
Peripheral embolism24.01.02.0050.007095%Not Available
Cardiac valve disease02.07.02.0010.000856%Not Available
Venous thrombosis limb24.01.02.0090.001933%Not Available
Gastrointestinal ulcer07.04.04.0020.000856%Not Available
Polyp16.02.02.005; 08.01.06.0100.003132%Not Available
Urinary tract obstruction20.08.01.0040.000856%
Ulcer haemorrhage08.03.06.003; 24.07.01.0400.002080%Not Available
Cardiac fibrillation02.03.02.0210.000367%Not Available
Artery dissection24.02.01.0030.000245%Not Available
Autoimmune disorder10.04.04.0030.000783%
Diverticular perforation07.04.04.0080.000856%Not Available
Obstruction08.01.03.0230.000489%Not Available
Oesophageal neoplasm07.21.04.004; 16.13.08.0010.000245%Not Available
Gastrointestinal obstruction07.13.01.0050.000612%Not Available
Lung neoplasm22.08.01.006; 16.19.04.0010.000489%Not Available
Large intestinal obstruction07.13.03.0030.000734%
Metabolic encephalopathy17.13.01.001; 14.11.01.0130.000612%Not Available
Renal impairment20.01.03.0100.029799%Not Available
Non-cardiac chest pain22.12.02.009; 08.01.08.0060.000489%
Heparin-induced thrombocytopenia24.01.01.020; 10.02.01.007; 01.08.01.0040.000489%Not Available
Peripheral arterial occlusive disease24.04.03.0100.000734%Not Available
Arterial occlusive disease24.04.02.0210.001101%Not Available
Haemorrhagic diathesis24.07.01.020; 01.01.03.0030.001223%Not Available
Effusion08.01.03.0520.000538%Not Available
Cerebral artery stenosis17.08.02.010; 24.04.06.0230.000367%Not Available
Erosive oesophagitis07.04.05.0040.000245%Not Available
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