Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cloxacillin
Drug ID BADD_D00510
Description A semi-synthetic penicillin antibiotic which is a chlorinated derivative of [oxacillin].
Indications and Usage Used to treat infections caused by penicillinase-producing staphylococci, including pneumococci, group A beta-hemolytic streptococci, and penicillin G-sensitive and penicillin G-resistant staphylococci.
Marketing Status Discontinued
ATC Code J01CF02
DrugBank ID DB01147
KEGG ID D07733
MeSH ID D003023
PubChem ID 6098
TTD Drug ID D04KTZ
NDC Product Code Not Available
Synonyms Cloxacillin | Chloroxacillin | Syntarpen | Tegopen | Cloxacillin Sodium | Sodium, Cloxacillin | Sodium Cloxacillin | Cloxacillin, Sodium
Chemical Information
Molecular Formula C19H18ClN3O5S
CAS Registry Number 61-72-3
SMILES CC1=C(C(=NO1)C2=CC=CC=C2Cl)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Thrombocytopenia01.08.01.002--Not Available
Thrombocytopenic purpura23.06.01.007; 01.08.01.003--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vascular purpura23.06.01.008; 01.01.04.007; 24.07.06.011--Not Available
Vomiting07.01.07.003--
Musculoskeletal discomfort15.03.04.001--Not Available
Candida infection11.03.03.021--
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