Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Clorazepate dipotassium
Drug ID BADD_D00506
Description A water-soluble benzodiazepine derivative effective in the treatment of anxiety. It has also muscle relaxant and anticonvulsant actions.
Indications and Usage For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Also used as adjunctive therapy in the management of partial seizures and for the symptomatic relief of acute alcohol withdrawal.
Marketing Status Prescription; Discontinued
ATC Code N05BA05
DrugBank ID DB00628
KEGG ID D00694
MeSH ID D003009
PubChem ID 167305
TTD Drug ID D0P3JU
NDC Product Code 0378-0040; 0378-0070; 43063-030; 55292-304; 51672-4042; 51672-4044; 13107-321; 51672-4043; 43063-893; 13107-319; 13107-320; 0378-0030; 12828-0019; 69037-0067
Synonyms Clorazepate Dipotassium | Dipotassium Chlorazepate | 4306-CB | Chlorazepate | Clorazepate | Tranxene | Tranxilium | Clorazepic Acid | Clorazepate Monopotassium
Chemical Information
Molecular Formula C16H11ClK2N2O4
CAS Registry Number 57109-90-7
SMILES C1=CC=C(C=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)C(=O)[O-].[OH-].[K+].[K+]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Ataxia17.02.02.001; 08.01.02.004--
Blood pressure systolic decreased13.14.03.007--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Depression19.15.01.001--
Diplopia17.17.01.005; 06.02.06.002--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Dysarthria19.19.03.001; 17.02.08.001--
Fatigue08.01.01.002--
Gastrointestinal disorder07.11.01.001--Not Available
Haematocrit decreased13.01.05.001--Not Available
Headache17.14.01.001--
Insomnia19.02.01.002; 17.15.03.002--
Irritability19.04.02.013; 08.01.03.011--
Liver function test abnormal13.03.01.013--Not Available
Nervousness19.06.02.003--Not Available
Rash23.03.13.001--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Tremor17.01.06.002--
Vision blurred17.17.01.010; 06.02.06.007--
Renal impairment20.01.03.010--Not Available
Genital discomfort21.10.01.007--Not Available
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