Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Citalopram hydrobromide
Drug ID BADD_D00476
Description Citalopram belongs to a class of antidepressant agents known as selective _serotonin-reuptake inhibitors_ (SSRIs) and is widely used to treat the symptoms of depression. Its chemical structure is unrelated to that of other SSRIs or of tricyclic, tetracyclic, or other prescribed antidepressants [FDA label]. Citalopram is also known as _Celexa_, and available in tablet and solution forms [FDA label]. This drug was initially approved by the FDA in 1998 [L5230].
Indications and Usage For the treatment of depression. Off-label indications include: treatment of mild dementia-associated agitation in nonpsychotic patients, smoking cessation, ethanol abuse, obsessive-compulsive disorder (OCD) in children, and diabetic neuropathy [FDA label].
Marketing Status Prescription
ATC Code N06AB04
DrugBank ID DB00215
KEGG ID D00822
MeSH ID D015283
PubChem ID 77995
TTD Drug ID D0Y5DO
NDC Product Code 13668-010; 71610-413; 63187-220; 58118-0023; 68645-569; 50090-3498; 50090-1298; 71335-0377; 70934-127; 70934-431; 68788-8962; 68071-4604; 65977-0018; 43063-481; 57664-509; 68071-2459; 65862-007; 0456-4021; 47621-022; 65862-005; 50090-3208; 51655-664; 65015-721; 71335-0480; 68071-2523; 50090-3136; 55700-838; 55154-3349; 61919-480; 59349-0010; 70934-842; 68645-570; 53002-1359; 13668-009; 61919-055; 68084-744; 53002-1579; 72657-111; 43063-670; 13668-011; 64220-105; 72657-110; 53002-2359; 68071-4123; 55700-851; 54838-540; 70518-0542; 68071-1906; 72761-006; 68788-0802; 70934-090; 68788-9692; 0615-8141; 55486-1572; 55111-902; 72789-071; 0904-6086; 0904-6085; 0456-4041; 61919-259; 65862-317; 31722-564; 43063-683; 70518-0070; 71335-0573; 60760-009; 0615-8022; 68645-559; 55111-343; 68645-571; 68071-3084; 42708-019; 0904-6084; 42708-091; 70518-1357; 65862-336; 51655-667; 68084-737; 65977-0053; 65372-1101; 70518-1917; 0615-8023; 17856-0564; 72657-109; 55154-3329; 55111-342; 65862-006; 63187-140; 68071-1830; 63629-8225; 63187-203; 53002-1360; 55700-787; 68071-2198; 50090-0892; 65862-074; 70934-304; 67296-1186; 53104-7738; 65372-1130; 51655-043; 71335-0238; 68071-5132; 55111-344; 68071-4324; 0456-4011; 53002-2360; 22365-112; 63187-679; 57664-507; 57664-508
Synonyms Citalopram | Cytalopram | Citalopram Hydrobromide | Lu-10-171 | Lu10171 | Seropram | Celexa
Chemical Information
Molecular Formula C20H22BrFN2O
CAS Registry Number 59729-32-7
SMILES CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F.Br
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Poisoning and toxicityCytochrome P450 2D6P10635T57392Not Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Diplopia17.17.01.005; 06.02.06.002--Not Available
Disturbance in attention19.21.02.002; 17.03.03.001--
Diverticulitis11.01.07.003; 07.10.02.001--Not Available
Dizziness02.01.02.004; 24.06.02.007; 17.02.05.003--
Drug dependence19.07.02.009--Not Available
Dry eye06.08.02.001--
Dry mouth07.06.01.002--
Dry skin23.03.03.001--
Duodenal ulcer07.04.02.002--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyskinesia17.01.02.006--
Dysmenorrhoea21.01.01.002--
Dyspepsia07.01.02.001--
Dysphagia07.01.06.003--
Dyspnoea02.01.03.002; 22.02.01.004--
Dystonia17.01.03.001--Not Available
Dysuria20.02.02.002--
Ecchymosis24.07.06.002; 23.06.01.001; 01.01.03.001--Not Available
Eczema23.03.04.006--
Ejaculation disorder21.03.01.002--
Electrocardiogram QT prolonged13.14.05.004--
Epistaxis24.07.01.005; 22.04.03.001--
Eructation07.01.02.003--
Erythema multiforme23.03.01.003; 10.01.03.015--
Euphoric mood19.04.02.006--
Extrapyramidal disorder17.01.02.007--
Extrasystoles02.03.02.003--Not Available
Eye pain06.08.03.002--
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