Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Citalopram
Drug ID BADD_D00475
Description Citalopram belongs to a class of antidepressant agents known as selective _serotonin-reuptake inhibitors_ (SSRIs) and is widely used to treat the symptoms of depression. Its chemical structure is unrelated to that of other SSRIs or of tricyclic, tetracyclic, or other prescribed antidepressants [FDA label]. Citalopram is also known as _Celexa_, and available in tablet and solution forms [FDA label]. This drug was initially approved by the FDA in 1998 [L5230].
Indications and Usage For the treatment of depression, as indicated by the FDA label [FDA label]. Off-label indications include but are not limited to: treatment of sexual dysfunction, post-stroke behavioural changes, ethanol abuse, obsessive-compulsive disorder (OCD) in children, and diabetic neuropathy [FDA label], [A321], [A322], [A323], [A324], [A174406], [A174409], [A174412].
Marketing Status approved
ATC Code N06AB04
DrugBank ID DB00215
KEGG ID D07704
MeSH ID D015283
PubChem ID 2771
TTD Drug ID D0Y5DO
NDC Product Code 42806-020; 71335-0541; 76282-206; 80425-0093; 37662-0340; 43353-091; 54458-980; 0054-0062; 70518-2601; 63850-3616; 0456-4040; 68071-3034; 68788-7899; 70518-2228; 76282-207; 76282-629; 43353-112; 43353-208; 50090-5172; 50090-5175; 61919-390; 0378-6231; 69097-822; 69097-824; 71610-092; 37662-0341; 37662-0342; 52427-691; 65162-053; 0378-6233; 69097-823; 60429-175; 62135-540; 65162-052; 0378-6232; 70518-2553; 70518-2617; 70518-2671; 37662-0339; 37662-0343; 50090-5170; 51655-137; 60429-173; 60429-174; 61919-389; 0456-4020; 42806-021; 54458-889; 54458-981; 65162-054; 0456-4010; 76282-628; 37662-0337; 37662-0338; 42806-019; 51655-938; 71610-412; 71610-422; 76282-208; 37662-0336; 43063-063; 51655-209
UNII 0DHU5B8D6V
Synonyms Citalopram | Cytalopram | Citalopram Hydrobromide | Lu-10-171 | Lu10171 | Seropram | Celexa
Chemical Information
Molecular Formula C20H21FN2O
CAS Registry Number 59729-33-8
SMILES CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Breast swelling21.05.05.0080.000065%Not Available
Bronchitis22.07.01.001; 11.01.09.001--
Bronchospasm22.03.01.004; 10.01.03.012--
Bruxism19.11.03.001; 07.01.06.0080.000061%Not Available
Bundle branch block02.03.01.009--Not Available
Bundle branch block left02.03.01.0070.000029%Not Available
Bundle branch block right02.03.01.0110.000019%Not Available
Burning sensation17.02.06.001; 08.01.09.0290.000019%Not Available
Bursitis12.04.03.010; 15.04.01.001--Not Available
Cardiac arrest02.03.04.0010.000086%
Cardiac failure02.05.01.001--
Cardiac failure congestive02.05.01.0020.000116%Not Available
Cardio-respiratory arrest02.03.04.002; 22.02.06.0070.000038%Not Available
Cardiovascular disorder02.11.01.010; 24.03.02.009--Not Available
Cataract06.06.01.001--
Catatonia19.11.01.001--Not Available
Cellulitis23.11.02.004; 11.02.01.001--Not Available
Cerebral atrophy17.11.01.0010.000019%Not Available
Cerebral haemorrhage24.07.04.001; 17.08.01.0030.000019%Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Cerebrovascular disorder24.03.05.002; 17.08.02.002--Not Available
Chest discomfort22.12.02.002; 08.01.08.019; 02.02.02.009--Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.0110.000067%Not Available
Chills15.05.03.016; 08.01.09.001--
Cholecystitis09.03.01.001--
Cholecystitis chronic09.03.01.0040.000019%Not Available
Cholelithiasis09.03.01.002--Not Available
Choreoathetosis17.01.01.003--Not Available
Coagulopathy01.01.02.001--Not Available
Colitis07.08.01.001--
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ADReCS-Target
Drug Name ADR Term Target
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