Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ciclesonide
Drug ID BADD_D00460
Description Ciclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco.
Indications and Usage For the treatment of nasal symptoms associated with seasonal and perennial allergic rhinitis in adults and adolescents 12 years of age and older.
Marketing Status Prescription
ATC Code R01AD13; R03BA08
DrugBank ID DB01410
KEGG ID D01703
MeSH ID C120481
PubChem ID 6918155
TTD Drug ID D0K7HU
NDC Product Code 70515-701; 64918-1900; 53104-7633; 70515-712; 24002-0016; 70515-711; 70515-737; 64918-1112
Synonyms ciclesonide | (R)-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclohexanecarboxaldehyde, 21-isobutyrate | Alvesco | Omnaris
Chemical Information
Molecular Formula C32H44O7
CAS Registry Number 126544-47-6
SMILES CC(C)C(=O)OCC(=O)C12C(CC3C1(CC(C4C3CCC5=CC(=O)C=CC45C)O)C)OC(O2)C6CCCCC6
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dyspepsia07.01.02.001--
Dysphonia22.02.05.005; 19.19.03.002; 17.02.08.004--
Dyspnoea22.02.01.004; 02.01.03.0020.011779%
Dyspnoea exertional22.02.01.005; 02.01.03.0030.003926%Not Available
Ear infection11.01.05.001; 04.03.01.006--Not Available
Ear pain04.03.01.003--
Epistaxis24.07.01.005; 22.04.03.001--
Eye discharge06.04.05.0010.001570%Not Available
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.0030.001570%
Fatigue08.01.01.002--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.0250.001570%
Fracture12.04.02.001; 15.08.02.001--
Gamma-glutamyltransferase increased13.03.01.011--
Gastroenteritis11.01.07.004; 07.19.03.001--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Haemoglobin13.01.05.018--Not Available
Hallucination, visual19.10.02.0040.001570%Not Available
Headache17.14.01.0010.004711%
Heart rate increased13.14.04.0020.001570%Not Available
Hyperadrenocorticism05.01.01.003; 24.08.02.005; 14.11.01.009--Not Available
Hypersensitivity10.01.03.0030.003926%
Hypertension24.08.02.001--
Immune system disorder10.02.01.001--Not Available
Impaired healing08.03.02.001--Not Available
Infection11.01.08.002--Not Available
Influenza22.07.02.001; 11.05.03.001--Not Available
Insomnia19.02.01.002; 17.15.03.0020.001570%
Intraocular pressure increased13.07.04.002--Not Available
Laboratory test abnormal13.18.01.001--Not Available
Laryngeal pain22.02.05.036--
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