Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Chlorphenamine
Drug ID BADD_D00444
Description A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Indications and Usage For the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever.
Marketing Status approved
ATC Code R06AB04
DrugBank ID DB01114
KEGG ID D07398
MeSH ID D002744
PubChem ID 2725
TTD Drug ID D0B7NG
NDC Product Code Not Available
UNII 3U6IO1965U
Synonyms Chlorpheniramine | Chlorprophenpyridamine | Chlorphenamine | Aller-Chlor | Antihistaminico Llorens | Chlor-100 | Chlor-Trimeton | Cloro-Trimeton | Chlorpheniramine Maleate | Maleate, Chlorpheniramine | Chlorpheniramine Tannate | Tannate, Chlorpheniramine | Chlorpro | Chlorspan 12 | Chlortab-4 | Efidac 24 | Kloromin | Piriton | Teldrin | Chlo-Amine | Chlor-Tripolon
Chemical Information
Molecular Formula C16H19ClN2
CAS Registry Number 113-92-8
SMILES CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agitation19.06.02.001; 17.02.05.012--
Agranulocytosis01.02.03.001--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001--Not Available
Anxiety19.06.02.002--
Asthenia08.01.01.001--Not Available
Chest discomfort22.12.02.002; 08.01.08.019; 02.02.02.009--Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Chills15.05.03.016; 08.01.09.001--
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Conversion disorder19.24.01.001--Not Available
Diarrhoea07.02.01.001--
Diplopia17.17.01.005; 06.02.06.002--Not Available
Disturbance in attention19.21.02.002; 17.03.03.001--
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Drug eruption23.03.05.001; 10.01.01.005; 08.01.06.015--Not Available
Dry mouth07.06.01.002--
Dyskinesia17.01.02.006--
Dyspepsia07.01.02.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Erythema23.03.06.001--Not Available
Euphoric mood19.04.02.006--
Extrasystoles02.03.02.003--Not Available
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Haemolytic anaemia01.06.03.002--Not Available
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