Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Chlorphenamine
Drug ID BADD_D00444
Description A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Indications and Usage For the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever.
Marketing Status OTC; Discontinued
ATC Code R06AB04
DrugBank ID DB01114
KEGG ID D07398
MeSH ID D002744
PubChem ID 2725
TTD Drug ID D0B7NG
NDC Product Code Not Available
Synonyms Chlorpheniramine | Chlorprophenpyridamine | Chlorphenamine | Aller-Chlor | Antihistaminico Llorens | Chlor-100 | Chlor-Trimeton | Cloro-Trimeton | Chlorpheniramine Maleate | Maleate, Chlorpheniramine | Chlorpheniramine Tannate | Tannate, Chlorpheniramine | Chlorpro | Chlorspan 12 | Chlortab-4 | Efidac 24 | Kloromin | Piriton | Teldrin | Chlo-Amine | Chlor-Tripolon
Chemical Information
Molecular Formula C16H19ClN2
CAS Registry Number 113-92-8
SMILES CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agitation19.06.02.001; 17.02.05.012--
Agranulocytosis01.02.03.001--Not Available
Anxiety19.06.02.002--
Asthenia08.01.01.001--Not Available
Chest discomfort08.01.08.019; 02.02.02.009; 22.02.08.001--Not Available
Chills15.05.03.016; 08.01.09.001--
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Conversion disorder19.24.01.001--Not Available
Diarrhoea07.02.01.001--
Diplopia17.17.01.005; 06.02.06.002--Not Available
Disturbance in attention19.21.02.002; 17.03.03.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Drug eruption08.01.06.015; 23.03.05.001; 10.01.01.005--Not Available
Dry mouth07.06.01.002--
Dyskinesia17.01.02.006--
Dyspepsia07.01.02.001--
Euphoric mood19.04.02.006--
Extrasystoles02.03.02.003--Not Available
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Haemolytic anaemia01.06.03.002--Not Available
Hallucination19.10.02.002--
Headache17.14.01.001--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypertension24.08.02.001--
Hypoplastic anaemia01.03.03.006--Not Available
Hyporeflexia17.02.01.003--
Hypotension24.06.03.002--
Insomnia19.02.01.002; 17.15.03.002--
The 1th Page    1 2    Next   Last    Total 2 Pages