Drug Name |
Chloroquine |
Drug ID |
BADD_D00440 |
Description |
Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria.[A191655] It was the drug of choice to treat malaria until the development of newer antimalarials such as [pyrimethamine], [artemisinin], and [mefloquine].[A191787] Chloroquine and its derivative [hydroxychloroquine] have since been repurposed for the treatment of a number of other conditions including HIV, systemic lupus erythematosus, and rheumatoid arthritis.[A192432]
**The FDA emergency use authorization for [hydroxychloroquine] and chloroquine in the treatment of COVID-19 was revoked on 15 June 2020.[L14312]**
Chloroquine was granted FDA Approval on 31 October 1949.[L12054] |
Indications and Usage |
For the suppressive treatment and for acute attacks of malaria due to P. vivax, P.malariae, P. ovale, and susceptible strains of P. falciparum, Second-line agent in treatment of Rheumatoid Arthritis |
Marketing Status |
Not Available |
ATC Code |
P01BA01 |
DrugBank ID |
DB00608
|
KEGG ID |
D02366
|
MeSH ID |
D002738
|
PubChem ID |
2719
|
TTD Drug ID |
D09EGZ
|
NDC Product Code |
Not Available |
Synonyms |
Chloroquine | Chlorochin | Chingamin | Khingamin | Nivaquine | Chloroquine Sulfate | Sulfate, Chloroquine | Chloroquine Sulphate | Sulphate, Chloroquine | Aralen | Arequin | Arechine |