Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Chlordiazepoxide hydrochloride
Drug ID BADD_D00433
Description An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
Indications and Usage For the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety.
Marketing Status Discontinued; Prescription
ATC Code N05BA02
DrugBank ID DB00475
KEGG ID D00693
MeSH ID D002707
PubChem ID 9916
TTD Drug ID D06BEP
NDC Product Code 55154-5652; 58118-1033; 42806-562; 43353-699; 43353-969; 58118-1590; 43547-251; 43547-253; 48087-0129; 70518-3134; 51079-141; 70518-1752; 70518-0015; 0555-0033; 42806-565; 48087-4401; 68071-5171; 42806-564; 43547-252; 0555-0159; 43063-046; 12828-0004; 63629-4027; 42806-566; 17856-0164; 50090-0328; 42806-563; 0555-0158
Synonyms Chlordiazepoxide | 7-Chloro-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-amine 4-oxide | 7 Chloro N methyl 5 phenyl 3H 1,4 benzodiazepin 2 amine 4 oxide | Methaminodiazepoxide | 7-Chloro-2-methylamino-5-phenyl-3H-1,4-benzodiazepine-4-oxide | 7 Chloro 2 methylamino 5 phenyl 3H 1,4 benzodiazepine 4 oxide | Chlordiazepoxide Hydrochloride | Hydrochloride, Chlordiazepoxide | Chlordiazepoxide Monohydrochloride | Monohydrochloride, Chlordiazepoxide | Librium | Chlozepid | Elenium | Chlordiazepoxide Hydrobromide | Hydrobromide, Chlordiazepoxide | Chlordiazepoxide Perchlorate | Perchlorate, Chlordiazepoxide
Chemical Information
Molecular Formula C16H14ClN3O.ClH
CAS Registry Number 438-41-5
SMILES CN=C1CN(C(=C2C=C(C=CC2=N1)Cl)C3=CC=CC=C3)O.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agranulocytosis01.02.03.001--Not Available
Ataxia17.02.02.001; 08.01.02.004--
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Electroencephalogram abnormal13.07.03.001--Not Available
Extrapyramidal disorder17.01.02.007--
Hepatic function abnormal09.01.02.001--Not Available
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Menstrual disorder21.01.01.004--Not Available
Nausea07.01.07.001--
Oedema08.01.07.006; 14.05.06.010--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Toxic skin eruption23.03.05.003; 10.01.01.008--Not Available
Libido disorder21.03.02.006; 19.08.03.004--Not Available
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