Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Chloral hydrate
Drug ID BADD_D00428
Description A hypnotic and sedative used in the treatment of insomnia. The safety margin is too narrow for chloral hydrate to be used as a general anesthetic in humans, but it is commonly used for that purpose in animal experiments. It is no longer considered useful as an anti-anxiety medication.
Indications and Usage Mainly used as a hyponotic in the treatment of insomnia; however, it is only effective as a hypnotic for short-term use. May be used as a routine sedative preoperatively to decrease anxiety and cause sedation and/or sleep with respiration depression or cough reflex.
Marketing Status Not Available
ATC Code N05CC01
DrugBank ID DB01563
KEGG ID D00265
MeSH ID D002697
PubChem ID 2707
TTD Drug ID D02OAV
NDC Product Code 65319-1224; 51552-0528; 38779-0641; 76003-0294; 51927-0122; 51927-1002
Synonyms Chloral Hydrate | Hydrate, Chloral | Noctec
Chemical Information
Molecular Formula C2H3Cl3O2
CAS Registry Number 302-17-0
SMILES C(C(Cl)(Cl)Cl)(O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Angioedema23.04.01.001; 10.01.05.009--Not Available
Ataxia08.01.02.004; 17.02.02.001--
Dermatitis bullous23.03.01.002--
Diarrhoea07.02.01.001--
Disorientation19.13.01.002; 17.02.05.015--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Eczema23.03.04.006--
Erythema multiforme23.03.01.003; 10.01.03.015--
Hangover08.01.09.018--Not Available
Nausea07.01.07.001--
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Pyrexia08.05.02.003--
Rash erythematous23.03.06.003--Not Available
Rash scarlatiniform23.03.13.006--Not Available
Sedation17.02.04.005--Not Available
Somnambulism19.02.03.006; 17.15.02.004--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vomiting07.01.07.003--
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