Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Cefuroxime
Drug ID BADD_D00407
Description Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Indications and Usage For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.
Marketing Status approved
ATC Code J01DC02; S01AA27
DrugBank ID DB01112
KEGG ID D00262
MeSH ID D002444
PubChem ID 41375
TTD Drug ID D0Y2IE
NDC Product Code 0143-9567; 0143-9569; 0143-9976; 0143-9568; 0143-9977; 0143-9979
UNII O1R9FJ93ED
Synonyms Cefuroxime | Cephuroxime | Zinacef | Ketocef
Chemical Information
Molecular Formula C16H16N4O8S
CAS Registry Number 55268-75-2
SMILES CON=C(C1=CC=CO1)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Stillbirth08.04.01.006; 18.01.02.0020.000215%Not Available
Stomatitis07.05.06.005--
Sudden death08.04.01.003; 02.03.04.0130.000286%
Swelling08.01.03.0150.000844%Not Available
Swelling face08.01.03.100; 23.04.01.018; 10.01.05.0180.000873%Not Available
Swollen tongue23.04.01.014; 10.01.05.015; 07.14.02.0030.000315%Not Available
Syncope02.11.04.015; 24.06.02.012; 17.02.04.0080.000572%
Tachycardia02.03.02.0070.001459%Not Available
Tachypnoea22.02.01.0140.000429%Not Available
Testicular pain21.13.01.0050.000143%
Thirst14.03.02.007; 08.01.09.0210.000143%Not Available
Throat irritation22.12.03.029; 07.05.05.0370.000529%Not Available
Throat tightness22.12.03.031; 19.01.02.0050.000286%Not Available
Thrombocytopenia01.08.01.002--Not Available
Thrombophlebitis24.01.02.001--Not Available
Tinnitus17.04.07.004; 04.04.01.0020.000386%
Tongue coated07.14.02.011--Not Available
Tongue disorder07.14.01.002--Not Available
Toothache07.09.06.0010.000143%
Toxic epidermal necrolysis23.03.01.008; 12.03.01.015; 11.07.01.006; 10.01.01.0060.000787%
Tracheobronchitis11.01.09.020; 22.07.01.016--Not Available
Tremor17.01.06.0020.000715%
Trismus17.01.03.004; 15.05.04.004--
Type I hypersensitivity10.01.03.0060.000501%Not Available
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urethral disorder20.07.01.002--Not Available
Urethral pain20.02.02.014--Not Available
Urinary incontinence20.02.02.010; 17.05.01.0080.000286%
Urinary tract disorder20.08.01.001--Not Available
Urinary tract infection20.08.02.001; 11.01.14.004--
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ADReCS-Target
Drug Name ADR Term Target
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