Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cefuroxime
Drug ID BADD_D00407
Description Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Indications and Usage For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.
Marketing Status approved
ATC Code J01DC02; S01AA27
DrugBank ID DB01112
KEGG ID D00262
MeSH ID D002444
PubChem ID 41375
TTD Drug ID D0Y2IE
NDC Product Code 0143-9567; 0143-9569; 0143-9976; 0143-9568; 0143-9977; 0143-9979
UNII O1R9FJ93ED
Synonyms Cefuroxime | Cephuroxime | Zinacef | Ketocef
Chemical Information
Molecular Formula C16H16N4O8S
CAS Registry Number 55268-75-2
SMILES CON=C(C1=CC=CO1)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cough22.02.03.0010.001002%
Creatinine renal clearance decreased13.13.01.013--Not Available
Cutaneous vasculitis23.06.02.001; 10.02.02.003; 24.12.04.0080.000358%Not Available
Cyanosis23.06.04.005; 02.11.04.004; 24.03.01.007; 22.02.02.0070.000429%
Delirium19.13.02.0010.000286%
Depressed level of consciousness17.02.04.0020.000358%
Dermatitis23.03.04.0020.000143%Not Available
Dermatitis allergic23.03.04.003; 10.01.03.0140.001416%Not Available
Dermatitis bullous23.03.01.0020.000601%
Dermatitis diaper21.10.01.016; 23.03.04.005--Not Available
Dermatitis exfoliative23.03.07.001; 10.01.01.0040.000529%
Diarrhoea07.02.01.001--
Diarrhoea haemorrhagic24.07.02.004; 07.02.01.0020.000215%Not Available
Diplopia17.17.01.005; 06.02.06.002--Not Available
Disability26.01.01.003--Not Available
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Drug eruption23.03.05.001; 10.01.01.005; 08.01.06.0150.001660%Not Available
Drug hypersensitivity10.01.01.0010.008828%Not Available
Drug interaction08.06.03.0010.000572%Not Available
Dyspepsia07.01.02.001--
Dyspnoea02.11.05.003; 22.02.01.0040.005594%
Dysuria20.02.02.0020.000143%
Ear pain04.03.01.0030.000358%
Electrolyte imbalance14.05.01.0020.000143%Not Available
Emphysema22.01.02.0020.000143%Not Available
Enterocolitis07.08.03.0030.000143%
Eosinophilia01.02.04.0010.000744%
Epilepsy17.12.03.0020.000215%Not Available
Epistaxis24.07.01.005; 22.04.03.001--
Erythema23.03.06.0010.003191%Not Available
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ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene