Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cefpodoxime
Drug ID BADD_D00395
Description Cefpodoxime is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and Gram negative bacteria. Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime.
Indications and Usage For the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms.
Marketing Status Not Available
ATC Code J01DD13
DrugBank ID DB01416
KEGG ID D07650
MeSH ID C053268
PubChem ID 6335986
TTD Drug ID D0W6CA
NDC Product Code Not Available
Synonyms cefpodoxime | U 76253A | U-76,253A | RU 51746 | RU-51746 | R 3746 | R-3746 | R 3763 | R-3763
Chemical Information
Molecular Formula C15H17N5O6S2
CAS Registry Number 80210-62-4
SMILES COCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Toxic epidermal necrolysis23.03.01.008; 11.07.01.006; 12.03.01.015; 10.01.01.006--
Tremor17.01.06.002--
Urticaria23.04.02.001; 10.01.06.001--
Vaginal infection21.14.02.002; 11.01.10.002--
Vaginal inflammation21.14.02.001--
Vertigo17.02.12.002; 04.04.01.003--
Vomiting07.01.07.003--
Weight increased13.15.01.006--
Wheezing22.03.01.009--
Localised oedema08.01.07.011; 02.05.04.006; 14.05.06.009--
Protein urine present13.13.02.006--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Haemorrhage24.07.01.002--Not Available
Rectal tenesmus15.05.03.011; 07.03.03.001--Not Available
Vasodilation procedure25.03.01.001--Not Available
Bacterial infection11.02.01.005--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Ill-defined disorder08.01.03.049--Not Available
Penile infection21.09.03.003; 11.01.19.002--
Renal impairment20.01.03.010--Not Available
Liver injury09.01.07.022; 12.01.02.003--Not Available
Oral disorder07.05.01.005--Not Available
Anorectal discomfort07.03.03.003--Not Available
Vulvovaginal pain21.08.02.009--
Candida infection11.03.03.021--
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