Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cefaclor
Drug ID BADD_D00378
Description Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.
Indications and Usage For the treatment of certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections.
Marketing Status Prescription; Discontinued
ATC Code J01DC04
DrugBank ID DB00833
KEGG ID D00256
MeSH ID D002433
PubChem ID 51039
TTD Drug ID D0PW7C
NDC Product Code 0093-1087; 0143-9985; 61442-172; 63629-1007; 23594-375; 61442-171; 23594-250; 0143-9986; 50090-1602; 23594-125
Synonyms Cefaclor | Cefaclor Anhydrous | Keclor | 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((aminophenylacetyl)amino)-3-chloro-8-oxo-, (6R-(6alpha,7beta(R*)))- | S-6472 | S 6472 | S6472 | Ceclor | Cefaclor Monohydrate | Lilly 99638
Chemical Information
Molecular Formula C15H14ClN3O4S
CAS Registry Number 53994-73-3
SMILES C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nephropathy toxic12.03.01.010; 20.05.03.002--Not Available
Nervous system disorder17.02.10.001--Not Available
Nervousness19.06.02.003--Not Available
Neutropenia01.02.03.004--Not Available
Nocturia20.02.03.001--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Oedema peripheral02.05.04.007; 08.01.07.007; 14.05.06.011--
Otitis media11.01.05.004; 04.05.01.001--
Pain08.01.08.004--
Palpitations02.01.02.003--
Pancytopenia01.03.03.003--Not Available
Paraesthesia17.02.06.005--
Platelet count decreased13.01.04.001--
Pneumonia22.07.01.003; 11.01.09.0030.000213%Not Available
Proteinuria20.02.01.011--
Prothrombin level increased13.01.02.011--Not Available
Prothrombin time prolonged13.01.02.012--Not Available
Pruritus23.03.12.001--
Pruritus genital23.03.12.008; 21.10.01.002--Not Available
Pseudomembranous colitis11.02.02.002; 07.19.01.003--Not Available
Psychomotor hyperactivity19.11.02.003; 17.01.02.011--Not Available
Pyrexia08.05.02.003--
Pyuria20.02.01.012; 11.01.08.043--Not Available
Rash23.03.13.0010.000213%Not Available
Rash generalised23.03.13.0020.000213%Not Available
Rash maculo-papular23.03.13.004--
Rash morbilliform23.03.13.005--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Seizure17.12.03.001--
Serum sickness12.02.08.004; 10.01.03.004--
The 4th Page    First    Pre   4 5 6    Next   Last    Total 6 Pages