| Pharmaceutical Information |
| Drug Name |
Caspofungin |
| Drug ID |
BADD_D00376 |
| Description |
Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. It is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall. |
| Indications and Usage |
For the treatment of esophageal candidiasis and invasive aspergillosis in patients who are refractory to or intolerant of other therapies. |
| Marketing Status |
Prescription |
| ATC Code |
J02AX04 |
| DrugBank ID |
DB00520
|
| KEGG ID |
D07626
|
| MeSH ID |
D000077336
|
| PubChem ID |
2826718
|
| TTD Drug ID |
D00ZCN
|
| NDC Product Code |
Not Available |
| Synonyms |
Caspofungin | Cancidas | MK 0991 | MK-0991 | MK0991 | Caspofungin MSD | L 743,872 | L-743,872 | L743,872 | L-743872 | L743872 | L 743872 | Caspofungin Acetate |
|
| Chemical Information |
| Molecular Formula |
C52H88N10O15 |
| CAS Registry Number |
162808-62-0 |
| SMILES |
CCC(C)CC(C)CCCCCCCCC(=O)NC1CC(C(NC(=O)C2C(CCN2C(=O)C(NC(=O)C(NC(=O)C3CC(CN3C(=O)
C(NC1=O)C(C)O)O)C(C(C4=CC=C(C=C4)O)O)O)C(CCN)O)O)NCCN)O |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
|
