Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Calcium gluconate
Drug ID BADD_D00340
Description Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. It can also be taken by mouth but is not recommended by injection into a muscle. Calcium Gluconate Injection, USP is a sterile, nonpyrogenic supersaturated solution of calcium gluconate for intravenous use only. Each mL contains: Calcium gluconate 94 mg; calcium saccharate (tetrahydrate) 4.5 mg; water for injection q.s. Hydrochloric acid and/or sodium hydroxide may have been added for pH adjustment (6.0 to 8.2). Calcium saccharate provides 6% of the total calcium and stabilizes the supersaturated solution of calcium gluconate. Each 10 mL of the injection provides 93 mg elemental calcium (Ca++) equivalent to 1 g of calcium gluconate.
Indications and Usage Oral calcium salts are used as dietary supplemental therapy for person who may not get enough calcium in their regular diet. Calcium gluconate is used as a cardioprotective agent in high blood potassium. Calcium gluconate is the antidote for magnesium sulfate toxicity.
Marketing Status Prescription
ATC Code A12AA03; D11AX03
DrugBank ID DB11126
KEGG ID D00935
MeSH ID D002125
PubChem ID 9290
TTD Drug ID Not Available
NDC Product Code 65219-164; 0295-7520; 51662-1347; 50090-3398; 64162-0448; 51662-1312; 44567-621; 71872-7222; 63323-360; 0404-9831; 52584-360; 65219-162; 44567-622; 44567-620
Synonyms Calcium Gluconate | Gluconate, Calcium | Calciofon | Calcium Braun | Calcivitol | Calglucon | CBG | Flopak Plain | Glucal | Glucobiogen | Gluconate de Calcium Lavoisier | Gluconato Calc Fresenius | Calcipot | Ebucin
Chemical Information
Molecular Formula C12H22CaO14
CAS Registry Number 299-28-5
SMILES C(C(C(C(C(C(=O)[O-])O)O)O)O)O.C(C(C(C(C(C(=O)[O-])O)O)O)O)O.[Ca+2]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abscess11.01.08.001--Not Available
Arrhythmia02.03.02.001--Not Available
Blood pressure decreased13.14.03.002--Not Available
Bradycardia02.03.02.002--Not Available
Cardiac arrest02.03.04.001--
Dysgeusia07.14.03.001; 17.02.07.003--
Necrosis24.04.02.006; 08.03.03.001--Not Available
Paraesthesia17.02.06.005--
Pyrexia08.05.02.003--
Sense of oppression08.01.09.020--Not Available
Syncope17.02.04.008; 02.01.02.008; 24.06.02.012--
Vasodilation procedure25.03.01.001--Not Available
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