Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Butorphanol tartrate
Drug ID BADD_D00325
Description A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Indications and Usage For the relief of moderate to severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AF01
DrugBank ID DB00611
KEGG ID D00837
MeSH ID D002077
PubChem ID 5462346
TTD Drug ID D0X9RG
NDC Product Code 38779-1765; 0143-9867; 0409-1626; 0143-9864; 47848-005; 60505-0813; 0409-1623; 0054-3090; 62991-3162; 51927-2986; 66651-920
Synonyms Butorphanol | 17-(Cyclobutylmethyl)morphinan-3,14-diol | BC-2627 | BC 2627 | BC2627 | Beforal | Butorphanol Tartrate | Moradol | Stadol | Stadol NS | Torbugesic | Apo-Butorphanol | Dolorex
Chemical Information
Molecular Formula C25H35NO8
CAS Registry Number 58786-99-5
SMILES C1CCC2(C3CC4=C(C2(C1)CCN3CC5CCC5)C=C(C=C4)O)O.C(C(C(=O)O)O)(C(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypertension24.08.02.001--
Hypopnoea22.02.01.021--Not Available
Hypotension24.06.03.002--
Insomnia19.02.01.002; 17.15.03.002--
Lethargy08.01.01.008; 19.04.04.004; 17.02.04.003--
Nasal congestion22.04.04.001--
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Palpitations02.01.02.003--
Paraesthesia17.02.06.005--
Pharyngitis11.01.13.003; 22.07.03.004; 07.05.07.004--
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Seizure17.12.03.001--
Sinus congestion22.04.06.001--Not Available
Sinusitis22.07.03.007; 11.01.13.005--
Somnolence19.02.05.003; 17.02.04.006--
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Tachycardia02.03.02.007--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Tremor17.01.06.002--
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urticaria23.04.02.001; 10.01.06.001--
Vertigo17.02.12.002; 04.04.01.003--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
Withdrawal syndrome19.07.02.005; 08.06.02.012--Not Available
Nasal discomfort22.02.05.020--Not Available
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