Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Butorphanol
Drug ID BADD_D00324
Description A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Indications and Usage For the relief of moderate to severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AF01
DrugBank ID DB00611
KEGG ID D03197
MeSH ID D002077
PubChem ID 5361092
TTD Drug ID D0X9RG
NDC Product Code Not Available
Synonyms Butorphanol | 17-(Cyclobutylmethyl)morphinan-3,14-diol | BC-2627 | BC 2627 | BC2627 | Beforal | Butorphanol Tartrate | Moradol | Stadol | Stadol NS | Torbugesic | Apo-Butorphanol | Dolorex
Chemical Information
Molecular Formula C21H29NO2
CAS Registry Number 42408-82-2
SMILES C1CCC2(C3CC4=C(C2(C1)CCN3CC5CCC5)C=C(C=C4)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Seizure17.12.03.001--
Shock24.06.02.002--Not Available
Sinus congestion22.04.06.001--Not Available
Sinusitis22.07.03.007; 11.01.13.005--
Somnolence19.02.05.003; 17.02.04.006--
Stupor17.02.04.007; 19.02.05.004--Not Available
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Tachycardia02.03.02.007--Not Available
Tension19.06.02.005--Not Available
Thinking abnormal19.10.03.001; 17.02.05.023--Not Available
Thirst14.03.02.007; 08.01.09.021--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Tremor17.01.06.002--
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urticaria10.01.06.001; 23.04.02.001--
Vertigo17.02.12.002; 04.04.01.003--
Vision blurred17.17.01.010; 06.02.06.007--
Visual impairment06.02.06.008--Not Available
Vomiting07.01.07.003--
Hypoacusis04.02.01.006--
Rhinalgia22.02.05.032--Not Available
Sticky skin23.03.03.019--Not Available
Nasal discomfort22.02.05.020--Not Available
Vasodilation procedure25.03.01.001--Not Available
Disturbance in sexual arousal19.08.04.003--Not Available
Poisoning12.03.01.004--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
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