Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Butorphanol
Drug ID BADD_D00324
Description A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Indications and Usage For the relief of moderate to severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AF01
DrugBank ID DB00611
KEGG ID D03197
MeSH ID D002077
PubChem ID 5361092
TTD Drug ID D0X9RG
NDC Product Code Not Available
Synonyms Butorphanol | 17-(Cyclobutylmethyl)morphinan-3,14-diol | BC-2627 | BC 2627 | BC2627 | Beforal | Butorphanol Tartrate | Moradol | Stadol | Stadol NS | Torbugesic | Apo-Butorphanol | Dolorex
Chemical Information
Molecular Formula C21H29NO2
CAS Registry Number 42408-82-2
SMILES C1CCC2(C3CC4=C(C2(C1)CCN3CC5CCC5)C=C(C=C4)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Drug effect increased08.06.01.011--Not Available
Drug effect prolonged08.06.01.012--Not Available
Drug withdrawal syndrome19.07.02.011; 08.06.02.004--Not Available
Dry mouth07.06.01.002--
Dysarthria19.19.03.001; 17.02.08.001--
Dyskinesia17.01.02.006--
Dysphagia07.01.06.003--
Dysphoria19.04.02.004--Not Available
Dyspnoea22.02.01.004; 02.01.03.002--
Ear disorder04.03.01.001--Not Available
Ear pain04.03.01.003--
Epistaxis24.07.01.005; 22.04.03.001--
Erythema23.03.06.001--Not Available
Euphoric mood19.04.02.006--
Eye disorder06.08.03.001--Not Available
Eye pain06.08.03.002--
Feeling abnormal08.01.09.014--Not Available
Feeling cold08.01.09.008--Not Available
Feeling hot08.01.09.009--Not Available
Flatulence07.01.04.002--
Gait disturbance17.02.05.016; 08.01.02.002--
Gastrointestinal pain07.01.05.005--
Hallucination19.10.02.002--
Headache17.14.01.001--
Hostility19.05.01.003--Not Available
Hyperacusis17.04.03.003; 04.02.02.001--Not Available
Hyperaesthesia17.02.06.004--Not Available
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypertension24.08.02.001--
Hypopnoea22.02.01.021--Not Available
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