| Pharmaceutical Information |
| Drug Name |
Butabarbital |
| Drug ID |
BADD_D00319 |
| Description |
Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.[A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety.[A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines.[A19735] Its short duration of action gives butabarbital a high abuse potential, comparable to [secobarbital].[A201977,A201980]
Butabarbital was granted FDA approval on 5 June 1939.[L13613] |
| Indications and Usage |
For short-term treatment of insomnia and anxiety disorders |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
Not Available |
| DrugBank ID |
DB00237
|
| KEGG ID |
D03180
|
| MeSH ID |
C084833
|
| PubChem ID |
2479
|
| TTD Drug ID |
D0A4JK
|
| NDC Product Code |
61960-2400 |
| Synonyms |
secbutabarbital | butabarbital | secumalum | butabarbitone | secbutobarbitone | Butisol Sodium | Butisol | Sarisol | secbutabarbital sodium | butabarbital sodium | 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylpropyl)-, monosodium salt |
|
| Chemical Information |
| Molecular Formula |
C10H16N2O3 |
| CAS Registry Number |
125-40-6 |
| SMILES |
CCC(C)C1(C(=O)NC(=O)NC1=O)CC |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Syncope | 17.02.04.008; 02.01.02.008; 24.06.02.012 | - | - | | | Tension | 19.06.02.005 | - | - | Not Available | | Vomiting | 07.01.07.003 | - | - | | | Liver injury | 12.01.02.003; 09.01.07.022 | - | - | Not Available |
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