Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Budesonide
Drug ID BADD_D00306
Description Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994.[L10598]
Indications and Usage The oral capsule is used for the treatment of mild to moderate active Crohn's disease. The oral tablet is used for induction of remission in patients with active, mild to moderate ulcerative colitis. The oral inhalation formulation is used for the treatment of asthma, non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis.
Marketing Status Prescription; OTC; Discontinued
ATC Code A07EA06; D07AC09; R01AD05; R03BA02
DrugBank ID DB01222
KEGG ID D00246
MeSH ID D019819
PubChem ID 5281004
TTD Drug ID D0Y7IU
NDC Product Code 0574-9850; 60505-6129; 0093-6815; 60687-596; 46122-389; 38779-3097; 21130-710; 60870-0466; 0093-6817; 0093-6816; 55566-1002; 49076-6111; 0363-0048; 51407-366; 0904-7166; 65162-778; 52128-133; 0591-2510; 0186-1988; 0186-1990; 51862-580; 0378-4500; 0487-9601; 47335-631; 63629-8294; 0781-7516; 15308-0100; 51508-004; 68788-7290; 0378-7155; 16714-018; 65089-0005; 52221-117; 76282-641; 81749-004; 49452-1292; 46439-8719; 60505-0839; 16714-829; 55154-4849; 65089-0024; 69097-318; 0574-9855; 68382-720; 65649-651; 76282-640; 38779-0198; 69097-321; 16714-020; 0115-1687; 76282-642; 55566-1020; 69842-001; 60429-264; 64918-0205; 49927-0004; 0186-1989; 10695-124; 50090-2239; 50580-646; 60505-6194; 71052-270; 51079-020; 51407-128; 68682-309; 0186-0916; 49452-1291; 16714-019; 68788-7314; 70771-1075; 68012-309; 0781-7517; 63592-0187; 0487-9701; 11822-1700; 50546-580; 63190-0060; 49035-703; 53183-6310; 53104-7617; 68743-309; 0781-7515; 73377-076; 47335-633; 0115-1689; 64918-0204; 69097-319; 0536-1112; 66412-0393; 51552-1365; 46439-8737; 68981-017; 47335-632; 0186-0917; 64980-255
Synonyms Budesonide | Budesonide, (S)-Isomer | Pulmicort | Rhinocort | Budesonide, (R)-Isomer | Horacort
Chemical Information
Molecular Formula C25H34O6
CAS Registry Number 51333-22-3
SMILES CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Urticaria23.04.02.001; 10.01.06.001--
Vascular purpura23.06.01.008; 01.01.04.007; 24.07.06.011--Not Available
Vasculitis24.05.02.001; 10.02.02.0060.000406%
Vertigo17.02.12.002; 04.04.01.003--
Viral infection11.05.04.001--Not Available
Viral upper respiratory tract infection22.07.02.004; 11.05.04.007--Not Available
Vision blurred17.17.01.010; 06.02.06.007--
Visual impairment06.02.06.0080.001625%Not Available
Vomiting07.01.07.003--
Weight decreased13.15.01.005--
Weight increased13.15.01.006--
Wheezing22.03.01.0090.005891%
White blood cell count increased13.01.06.0130.000609%Not Available
Mental status changes19.07.01.0010.000406%Not Available
Allergic granulomatous angiitis22.01.01.012; 24.05.02.010; 10.02.02.016; 01.02.04.009--Not Available
Histiocytosis haematophagic01.05.01.015; 10.02.01.0420.000159%Not Available
Red blood cell sedimentation rate increased13.01.03.001--Not Available
Bone density decreased13.16.01.0010.000406%Not Available
Oropharyngeal candidiasis07.05.07.003; 22.07.03.003; 11.03.03.006--Not Available
Contusion24.07.06.001; 23.03.11.002; 15.03.01.008; 12.01.06.0010.000609%
Plantar erythema23.03.06.0120.000609%Not Available
Viral diarrhoea11.05.04.012; 07.19.02.008--Not Available
Haemodynamic instability24.03.02.0060.000609%Not Available
Ear pruritus04.03.01.011--Not Available
Lymphatic disorder01.09.01.003--Not Available
Nasal discomfort22.02.05.0200.000406%Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Secretion discharge08.01.03.0190.000609%Not Available
Type IV hypersensitivity reaction10.01.03.0220.000406%Not Available
Growth retardation15.03.01.0060.001016%
The 12th Page    First    Pre   12 13 14 15    Next   Last    Total 15 Pages