Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Budesonide
Drug ID BADD_D00306
Description Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994.[L10598]
Indications and Usage The oral capsule is used for the treatment of mild to moderate active Crohn's disease. The oral tablet is used for induction of remission in patients with active, mild to moderate ulcerative colitis. The oral inhalation formulation is used for the treatment of asthma, non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis.
Marketing Status Prescription; OTC; Discontinued
ATC Code A07EA06; D07AC09; R01AD05; R03BA02
DrugBank ID DB01222
KEGG ID D00246
MeSH ID D019819
PubChem ID 5281004
TTD Drug ID D0Y7IU
NDC Product Code 0574-9850; 60505-6129; 0093-6815; 60687-596; 46122-389; 38779-3097; 21130-710; 60870-0466; 0093-6817; 0093-6816; 55566-1002; 49076-6111; 0363-0048; 51407-366; 0904-7166; 65162-778; 52128-133; 0591-2510; 0186-1988; 0186-1990; 51862-580; 0378-4500; 0487-9601; 47335-631; 63629-8294; 0781-7516; 15308-0100; 51508-004; 68788-7290; 0378-7155; 16714-018; 65089-0005; 52221-117; 76282-641; 81749-004; 49452-1292; 46439-8719; 60505-0839; 16714-829; 55154-4849; 65089-0024; 69097-318; 0574-9855; 68382-720; 65649-651; 76282-640; 38779-0198; 69097-321; 16714-020; 0115-1687; 76282-642; 55566-1020; 69842-001; 60429-264; 64918-0205; 49927-0004; 0186-1989; 10695-124; 50090-2239; 50580-646; 60505-6194; 71052-270; 51079-020; 51407-128; 68682-309; 0186-0916; 49452-1291; 16714-019; 68788-7314; 70771-1075; 68012-309; 0781-7517; 63592-0187; 0487-9701; 11822-1700; 50546-580; 63190-0060; 49035-703; 53183-6310; 53104-7617; 68743-309; 0781-7515; 73377-076; 47335-633; 0115-1689; 64918-0204; 69097-319; 0536-1112; 66412-0393; 51552-1365; 46439-8737; 68981-017; 47335-632; 0186-0917; 64980-255
Synonyms Budesonide | Budesonide, (S)-Isomer | Pulmicort | Rhinocort | Budesonide, (R)-Isomer | Horacort
Chemical Information
Molecular Formula C25H34O6
CAS Registry Number 51333-22-3
SMILES CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Small intestinal obstruction07.13.06.0010.000406%
Sneezing22.02.05.011--
Somnolence19.02.05.003; 17.02.04.006--
Speech disorder22.02.05.034; 19.19.02.002; 17.02.08.0030.000406%Not Available
Stomatitis07.05.06.0050.001219%
Stridor22.04.02.003--
Suffocation feeling22.02.08.0120.000406%Not Available
Swelling08.01.03.015--Not Available
Swelling face23.04.01.018; 10.01.05.0180.000406%Not Available
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Syndactyly15.11.07.015; 03.11.07.0150.000609%Not Available
Tachycardia02.03.02.0070.001625%Not Available
Tachypnoea22.02.01.0140.000609%Not Available
Tenderness08.01.08.005--Not Available
Tension19.06.02.005--Not Available
Tetany15.05.03.013; 14.04.01.005; 05.04.02.0030.000406%Not Available
Thirst14.03.02.007; 08.01.09.021--Not Available
Throat irritation22.02.05.013; 07.05.03.0040.000813%Not Available
Tic19.11.04.001; 17.02.05.0240.000406%Not Available
Tinnitus17.04.07.004; 04.04.01.0020.000609%
Tongue disorder07.14.01.002--Not Available
Tongue oedema23.04.01.009; 10.01.05.008; 07.14.02.007--Not Available
Tooth disorder07.09.05.001--Not Available
Tremor17.01.06.0020.001828%
Type I hypersensitivity10.01.03.0060.001016%Not Available
Ulcer08.03.06.001--Not Available
Upper respiratory tract infection22.07.03.011; 11.01.13.0090.001219%
Urethral disorder20.07.01.002--Not Available
Urinary tract disorder20.08.01.001--Not Available
Urinary tract infection20.08.02.001; 11.01.14.004--
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