Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Betaxolol hydrochloride
Drug ID BADD_D00264
Description A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Indications and Usage For the management of hypertension.
Marketing Status Prescription; Discontinued
ATC Code C07AB05; S01ED02
DrugBank ID DB00195
KEGG ID D00598
MeSH ID D015784
PubChem ID 107952
TTD Drug ID D03ROX
NDC Product Code 17478-705; 14445-002; 17337-0503; 59349-0005; 61314-245; 10702-014; 10702-013; 0065-0246
Synonyms Betaxolol | Betaxolol Hydrochloride | Hydrochloride, Betaxolol | Kerlone | Oxodal | Kerlon | SL-75212 | SL 75212 | SL75212 | ALO-1401-02 | ALO 1401 02 | ALO140102 | Betoptic | Betoptima | Betaxolol Alcon | Alcon, Betaxolol
Chemical Information
Molecular Formula C18H30ClNO3
CAS Registry Number 63659-19-8
SMILES CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Adverse drug reactionCytochrome P450 2D6P10635T57392Not Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Alopecia23.02.02.001--
Asthma22.03.01.002; 10.01.03.010--Not Available
Atrioventricular block02.03.01.002--Not Available
Bradycardia02.03.02.002--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Cardiac failure congestive02.05.01.002--Not Available
Depression19.15.01.001--
Discomfort08.01.08.003--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dyspnoea22.02.01.004; 02.01.03.002--
Erythema23.03.06.001--Not Available
Glossitis07.14.01.001--Not Available
Headache17.14.01.001--
Hypoaesthesia eye17.02.06.019; 06.01.01.007--Not Available
Insomnia17.15.03.002; 19.02.01.002--
Keratitis06.04.02.002--
Lacrimation increased06.08.02.004--
Lethargy19.04.04.004; 17.02.04.003; 08.01.01.008--
Myasthenia gravis15.05.08.001; 10.04.05.001; 17.05.04.001--
Oedema14.05.06.010; 08.01.07.006--Not Available
Photophobia17.17.02.006; 06.01.01.004--
Pruritus23.03.12.001--
Pupils unequal17.02.11.005; 06.05.03.005--Not Available
Respiratory failure22.02.06.002; 14.01.04.003--
Toxic epidermal necrolysis10.01.01.006; 23.03.01.008; 12.03.01.015; 11.07.01.006--
Urticaria23.04.02.001; 10.01.06.001--
Vertigo17.02.12.002; 04.04.01.003--
Vital dye staining cornea present13.07.04.010--Not Available
Increased bronchial secretion22.02.04.007--Not Available
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